(Q83338133)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16699172%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity (English)

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21 January 2020

1

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21 January 2020

author name string

Saturnino Herrero

2

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21 January 2020

Christine B Breitenlechner

3

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21 January 2020

Andrea Erlbruch

4

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21 January 2020

Wolf Lehmann

5

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21 January 2020

Richard A Engh

6

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21 January 2020

Michael Gassel

7

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21 January 2020

Dirk Bossemeyer

8

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21 January 2020

language of work or name

English

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publication date

12 May 2006

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Journal of Biological Chemistry

21 January 2020

published in

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21 January 2020

volume

281

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21 January 2020

issue

34

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21 January 2020

page(s)

24818-24830

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The Albert Lasker Medical Awards. Role of the cyclic AMP-dependent protein kinase in signal transduction

21 January 2020

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Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

21 January 2018

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The molecular genetics of cancer

21 January 2018

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Signal transduction and growth control in normal and cancer cells

21 January 2018

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The protein kinase complement of the human genome

21 January 2018

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

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The phosphorylation of proteins: a major mechanism for biological regulation. Fourteenth Sir Frederick Gowland Hopkins memorial lecture

21 January 2018

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Erlotinib in the treatment of non-small cell lung cancer

21 January 2018

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H-series protein kinase inhibitors and potential clinical applications

21 January 2018

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Regulation and functions of Rho-associated kinase

21 January 2018

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Anti-anginal effect of fasudil, a Rho-kinase inhibitor, in patients with stable effort angina: a multicenter study

21 January 2018

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Rocks: multifunctional kinases in cell behaviour

21 January 2018

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Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells

21 January 2018

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Rho/Rho-kinase mediated signaling in physiology and pathophysiology

21 January 2018

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Structural bioinformatics-based design of selective, irreversible kinase inhibitors

21 January 2018

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Protein kinase inhibitors: insights into drug design from structure.

21 January 2018

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Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants

21 January 2018

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Structure-based optimization of novel azepane derivatives as PKB inhibitors

21 January 2018

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Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity

21 January 2018

1 reference

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Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity

21 January 2018

1 reference

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Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

21 January 2018

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Purification and in vitro activity of Rho-associated kinase

21 January 2018

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Adenosine cyclic 3',5'-monophosphate dependent protein kinase: kinetic mechanism for the bovine skeletal muscle catalytic subunit

21 January 2018

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Creation and characterization of a new, non-redundant fragment data bank

21 January 2018

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Mutants of protein kinase A that mimic the ATP-binding site of protein kinase B (AKT)

21 January 2018

1 reference

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Essential role of rho kinase in the Ca2+ sensitization of prostaglandin F(2alpha)-induced contraction of rabbit aortae

21 January 2018

1 reference

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512374200

Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential

21 January 2018

1 reference

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Non-proline cis peptide bonds in proteins.

21 January 2018

1 reference

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Identification of electrostatic interactions that determine the phosphorylation site specificity of the cAMP-dependent protein kinase

21 January 2018

1 reference

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The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A.

21 January 2018

1 reference

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Properties and use of H-series compounds as protein kinase inhibitors

21 January 2018

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Characterization and purification of truncated human Rho-kinase II expressed in Sf-21 cells

21 January 2018

1 reference

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Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor.

21 January 2018

1 reference

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K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

21 January 2018

1 reference

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The novel and specific Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine as a probing molecule for Rho-kinase-involved pathway

21 January 2018

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Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

21 January 2018

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The structure of dimeric ROCK I reveals the mechanism for ligand selectivity

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M512374200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16699172%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference