(Q27670715)

English

Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes

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Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes (English)

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Bacillus anthracis

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based on heuristic

inferred from title

Andrzej Joachimiak

17

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Robert Jedrzejczak

8

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Magdalena Makowska-Grzyska

1

object named as

Magdalena Makowska-Grzyska

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14

object named as

Misty L Kuhn

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Wayne F. Anderson

15

object named as

Wayne F Anderson

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author name string

Magdalena Makowska-Grzyska

1

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Youngchang Kim

2

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Ruiying Wu

3

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Rosemarie Wilton

4

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Deviprasad R Gollapalli

5

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Ximi K Wang

6

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Rongguang Zhang

7

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Jamey C Mack

9

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Natalia Maltseva

10

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Rory Mulligan

11

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T Andrew Binkowski

12

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Piotr Gornicki

13

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Lizbeth Hedstrom

16

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language of work or name

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publication date

7 August 2012

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51

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31

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6148-63

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity

1 reference

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20 March 2017

IMP dehydrogenase: structure, mechanism, and inhibition

1 reference

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20 March 2017

An enzymatic atavist revealed in dual pathways for water activation

1 reference

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20 March 2017

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

1 reference

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20 March 2017

Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase

1 reference

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20 March 2017

Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Crystal structure of Tritrichomonas foetus inosine monophosphate dehydrogenase in complex with the inhibitor ribavirin monophosphate reveals a catalysis-dependent ion-binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Taking MAD to the extreme: ultrafast protein structure determination

1 reference

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20 March 2017

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1 reference

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20 March 2017

Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

The CCP4 suite: programs for protein crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

ARP/wARP and automatic interpretation of protein electron density maps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Substructure solution with SHELXD

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Inosine 5'-monophosphate dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

CBS domains: structure, function, and pathology in human proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Drug selectivity is determined by coupling across the NAD+ site of IMP dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

IMP dehydrogenase: mechanism of action and inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

20 March 2017

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1 reference

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7 April 2017

High-throughput protein purification and quality assessment for crystallization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Allosteric activation via kinetic control: potassium accelerates a conformational change in IMP dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

The antibiotic potential of prokaryotic IMP dehydrogenase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Inosine monophosphate dehydrogenase as a target for antiviral, anticancer, antimicrobial and immunosuppressive therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Structural determinants of inhibitor selectivity in prokaryotic IMP dehydrogenases

1 reference

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29 September 2017

Cleavable C-terminal His-tag vectors for structure determination.

1 reference

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29 September 2017

Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against cryptosporidiosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Inosine monophosphate dehydrogenase as a probe in antiviral drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Inosine monophosphate dehydrogenase (IMPDH) as a target in drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Monitoring of inosine monophosphate dehydrogenase activity as a biomarker for mycophenolic acid effect: potential clinical implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836674

29 September 2017

Optical biosensors: where next and how soon?

1 reference

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29 September 2017

IMP dehydrogenase: structural schizophrenia and an unusual base

1 reference

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29 September 2017

The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results.

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29 September 2017

Cryptosporidium parvum IMP dehydrogenase: identification of functional, structural, and dynamic properties that can be exploited for drug design

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Genetic complementation in apicomplexan parasites

1 reference

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29 September 2017

Mycophenolic Acid: a one hundred year odyssey from antibiotic to immunosuppressant

1 reference

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29 September 2017

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1 reference

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1 reference

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29 September 2017

Inhibition of IMPDH by mycophenolic acid: dissection of forward and reverse pathways using capillary electrophoresis

1 reference

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29 September 2017

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1 reference

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2 June 2018

Human IMP dehydrogenase catalyzes the dehalogenation of 2-fluoro- and 2-chloroinosine 5'-monophosphate in the absence of NAD.

1 reference

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2 June 2018

Federal Agency biodefense funding, FY2011-FY2012.

1 reference

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27 November 2018

Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity.

1 reference

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27 November 2018

Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia.

1 reference

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27 November 2018

Asp338 controls hydride transfer in Escherichia coli IMP dehydrogenase

1 reference

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27 November 2018

Monovalent cation activation in Escherichia coli inosine 5'-monophosphate dehydrogenase.

1 reference

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27 November 2018

Expression, purification, and characterization of inosine 5'-monophosphate dehydrogenase from Borrelia burgdorferi.

1 reference

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27 November 2018

Differential signatures of bacterial and mammalian IMP dehydrogenase enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22788966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mycophenolic acid; an antibiotic from Penicillium brevicompactum Dlerckx

1 reference

https://pubmed.ncbi.nlm.nih.gov/22788966

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI300511W

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release_6zpoyjz44fbflgeukh4d73pncy

1 reference

https://api.fatcat.wiki/v0/release/6zpoyjz44fbflgeukh4d73pncy

24 November 2022

based on heuristic

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