(Q27670838)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Fa Liu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Jung-Eun Park

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Dan Lim

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Martin Gräber

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Thorsten Berg

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Michael B Yaffe

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Kyung S Lee

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Terrence R Burke

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

publication date

17 July 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

595-601

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

From Crystal Packing to Molecular Recognition: Prediction and Discovery of a Binding Site on the Surface of Polo-Like Kinase 1

7 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Computational analysis of phosphopeptide binding to the polo-box domain of the mitotic kinase PLK1 using molecular dynamics simulation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Polo-like kinases: a team in control of the division

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Polo-like kinases and the orchestration of cell division

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Preparation of orthogonally protected (2S, 3R)-2-amino-3-methyl-4-phosphonobutyric acid (Pmab) as a phosphatase-stable phosphothreonine mimetic and its use in the synthesis of Polo-box domain-binding peptides

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Delivery of therapeutic proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

A case study from the chemistry core of the Pittsburgh Molecular Library Screening Center: the Polo-like kinase polo-box domain (Plk1-PBD).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

The natural product Aristolactam AIIIa as a new ligand targeting the polo-box domain of polo-like kinase 1 potently inhibits cancer cell proliferation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Mitsunobu and related reactions: advances and applications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

A pan-specific inhibitor of the polo-box domains of polo-like kinases arrests cancer cells in mitosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Polo-like kinases: conservation and divergence in their functions and regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Promiscuous aggregate-based inhibitors promote enzyme unfolding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Artificial oxygen carriers, hemoglobin vesicles and albumin-hemes, based on bioconjugate chemistry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Progress in the discovery of polo-like kinase inhibitors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Polo-like kinases (Plks) and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Regulation of cell cycle checkpoints by polo-like kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Polo-like kinases and oncogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Structure and function of Polo-like kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Polo-like kinases, an introduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Polo-like kinase 1 in the life and death of cancer cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Chemistry for peptide and protein PEGylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Functional studies on the role of the C-terminal domain of mammalian polo-like kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Pegnology: a review of PEG-ylated systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Mutation of the polo-box disrupts localization and mitotic functions of the mammalian polo kinase Plk.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158281

Targeting polo-like kinase 1 for cancer therapy.

29 September 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.614

The balance of Polo-like kinase 1 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.614

Inhibition of polo-like kinase 1 by blocking polo-box domain-dependent protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.614

A spindle checkpoint arrest and a cytokinesis failure by the dominant-negative polo-box domain of Plk1 in U-2 OS cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.614

Amphiphilic conjugates of human brain natriuretic peptide designed for oral delivery: in vitro activity screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.614

A dose range finding study of novel oral insulin (IN-105) under fed conditions in type 2 diabetes mellitus subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.614

Synthesis and antitumor activity of novel C-8 ester derivatives of leinamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.614

Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.614

The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21765407

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.614

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 February 2020

1004249165

0 references

Fatcat ID

release_sbjrsvtyv5cy3crqxd7kyezigu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sbjrsvtyv5cy3crqxd7kyezigu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21765407%20AND%20SRC:MED&resulttype=core&format=json