(Q27671443)

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Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition

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scholarly article

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Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition (English)

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crystal structure

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7

object named as

Faik N Musayev

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Mohini S Ghatge

3

object named as

Mohini S Ghatge

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10

object named as

Martin K Safo

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9

object named as

Verne Schirch

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Martino Luigi di Salvo

4

object named as

Martino L di Salvo

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Roberto Contestabile

8

object named as

Roberto Contestabile

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author name string

Amit K Gandhi

1

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Jigar V Desai

2

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Stefano Di Biase

5

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Richmond Danso-Danquah

6

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language of work or name

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publication date

2012

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7

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7

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e40954

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copyright license

Creative Commons Attribution 4.0 International

18 July 2012

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April 2022 Public Data File from Crossref

copyright status

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Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Crystal structure of human pyridoxal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Conformational changes in the reaction of pyridoxal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Crystal structure of brain pyridoxal kinase, a novel member of the ribokinase superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Overview of the CCP4 suite and current developments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Features and development of Coot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Human pyridoxal phosphatase. Molecular cloning, functional expression, and tissue distribution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Biosynthesis of 4'-O-methylpyridoxine (Ginkgotoxin) from primary precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Seizures induced by theophylline and isoniazid in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Roscovitine targets, protein kinases and pyridoxal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

20 March 2017

Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

7 April 2017

Ginkgo biloba and ginkgotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

Vitamin B6 status, deficiency and its consequences--an overview.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

The human pyridoxal kinase, a plausible target for ginkgotoxin from Ginkgo biloba

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

Isoniazid induced neuropathy: consider prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

B6-responsive disorders: a model of vitamin dependency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

Crystal structure of the PdxY Protein from Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

Depression of serum pyridoxal levels in theophylline-related seizures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

Update on interconversions of vitamin B-6 with its coenzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

Isoniazid-induced psychosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

Mechanisms of the inhibition of human erythrocyte pyridoxal kinase by drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

The toxicology of cocoa and methylxanthines: a review of the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

Genotoxicity of cocoa in a series of short-term assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

The relationship between vitamin B6 metabolism, asthma, and theophylline therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

29 September 2017

Crystal structure of pyridoxal kinase from the Escherichia coli pdxK gene: implications for the classification of pyridoxal kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

2 June 2018

Pyridoxine as therapy in theophylline-induced seizures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

2 June 2018

Vitamin B-6 supplementation and theophylline-related effects in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

2 June 2018

An antivitamin B6, 4'-methoxypyridoxine, from the seed of Ginkgo biloba L.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

2 June 2018

Genotoxicity of theobromine in a series of short-term assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

2 June 2018

Depression of vitamin B6 levels due to theophylline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

2 June 2018

Chronic toxicity/carcinogenicity studies of cocoa powder in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

2 June 2018

Differential decrease of GABA in the substantia nigra and other discrete regions of the rabbit brain during the preictal period of methoxypyridoxine-induced seizures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

2 June 2018

Case of an 81-year-old woman with theophylline-associated seizures followed by partial seizures due to vitamin B6 deficiency

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040954

21 January 2018

Ginkgo seed poisoning

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040954

21 January 2018

Activation of serum aminotransferases by pyridoxal-5' -phosphate in epileptic patients treated with anticonvulsant drugs

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040954

21 January 2018

Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040954

21 January 2018

Ginkgo seed food poisoning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

27 November 2018

Theophylline increases pyridoxal kinase activity independently from vitamin B6 nutritional status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

27 November 2018

Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

27 November 2018

Evidence of a theophylline-induced vitamin B6 deficiency caused by noncompetitive inhibition of pyridoxal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

27 November 2018

Altered vitamin B6 homeostasis during aminophylline infusion in the beagle dog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

27 November 2018

Inhibition of pyridoxal kinase by methylxanthines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

27 November 2018

Relationship between vitamin B-6 status and elevated pyridoxal kinase levels induced by theophylline therapy in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412620

27 November 2018

Depression of vitamin B6 levels due to dopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22879864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The crystal structure of an ADP complex of Bacillus subtilis pyridoxal kinase provides evidence for the parallel emergence of enzyme activity during evolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/22879864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0040954

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