(Q27676143)

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Molecular recognition at the active site of factor Xa: cation-π interactions, stacking on planar peptide surfaces, and replacement of structural water

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Molecular recognition at the active site of factor Xa: cation-π interactions, stacking on planar peptide surfaces, and replacement of structural water (English)

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François Diederich

10

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Laura M Salonen

object named as

Laura M Salonen

1

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Bernd Schweizer

8

object named as

W Bernd Schweizer

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Philip S J Kaib

3

object named as

Philip S J Kaib

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author name string

Mareike C Holland

2

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Wolfgang Haap

4

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Jörg Benz

5

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Jean-Luc Mary

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Olivier Kuster

7

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David W Banner

9

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language of work or name

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publication date

2 January 2012

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Chemistry—A European Journal

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18

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1

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213-22

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Structure of human des(1-45) factor Xa at 2.2 A resolution

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Probing the subpockets of factor Xa reveals two binding modes for inhibitors based on a 2-carboxyindole scaffold: a study combining structure-activity relationship and X-ray crystallography.

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Identifiers

10.1002/CHEM.201102571

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