(Q27676442)

English

Structural Insights into the Recovery of Aldolase Activity inN-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with γ-Thialysine by Using a Chemical Mutagenesis Strategy

scientific article

In more languages

Statements

scholarly article

0 references

Structural Insights into the Recovery of Aldolase Activity inN-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with γ-Thialysine by Using a Chemical Mutagenesis Strategy (English)

0 references

7

object named as

Adam Nelson

0 references

Arwen R Pearson

6

object named as

Arwen R Pearson

0 references

8

object named as

Alan Berry

0 references

object named as

Anna Polyakova

3

0 references

object named as

James R Ault

4

0 references

author name string

Nicole Timms

1

0 references

Claire L Windle

2

0 references

Chi H Trinh

5

0 references

publication date

4 March 2013

0 references

0 references

14

0 references

4

0 references

474-81

0 references

Structural Insights into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Structure of anEscherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 Å resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Kemp elimination catalysts by computational enzyme design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

De novo computational design of retro-aldol enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

A new UAG-encoded residue in the structure of a methanogen methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Structure and mechanism of a sub-family of enzymes related to N-acetylneuraminate lyase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

The three-dimensional structure of N-acetylneuraminate lyase from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Nucleotide sequence and expression of the selenocysteine-containing polypeptide of formate dehydrogenase (formate-hydrogen-lyase-linked) from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Features and development of Coot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Solving structures of protein complexes by molecular replacement with Phaser

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Scaling and assessment of data quality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

The integration of macromolecular diffraction data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Expanding the genetic code of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

Pyruvoyl-dependent enzymes

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

7 April 2017

Optimizing non-natural protein function with directed evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

29 September 2017

Directed evolution of aldolases for exploitation in synthetic organic chemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

29 September 2017

Directed evolution of enzymes for biocatalysis and the life sciences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

29 September 2017

Unnatural amino acid mutagenesis: a precise tool for probing protein structure and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

29 September 2017

The rate of hydrolysis of phosphomonoester dianions and the exceptional catalytic proficiencies of protein and inositol phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

29 September 2017

Chemical-modification rescue assessed by mass spectrometry demonstrates that gamma-thia-lysine yields the same activity as lysine in aldolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

29 September 2017

Novel cofactors via post-translational modifications of enzyme active sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

29 September 2017

A general method for site-specific incorporation of unnatural amino acids into proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

29 September 2017

Use of site-directed chemical modification to study an essential lysine in Escherichia coli leader peptidase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

2 June 2018

Decreasing the basicity of the active site base, Lys-258, of Escherichia coli aspartate aminotransferase by replacement with gamma-thialysine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

2 June 2018

Reengineering the catalytic lysine of aspartate aminotransferase by chemical elaboration of a genetically introduced cysteine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

2 June 2018

The mechanism of MIO-based aminomutases in beta-amino acid biosynthesis.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200714

21 January 2018

Creation of a pair of stereochemically complementary biocatalysts.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200714

21 January 2018

Structure-guided saturation mutagenesis of N-acetylneuraminic acid lyase for the synthesis of sialic acid mimetics.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200714

21 January 2018

Creation of a tailored aldolase for the parallel synthesis of sialic acid mimetics

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201200714

21 January 2018

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKa Predictions

2 references

https://api.crossref.org/works/10.1002%2FCBIC.201200714

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792637

27 November 2018

The critical active-site amine of the human 8-oxoguanine DNA glycosylase, hOgg1: direct identification, ablation and chemical reconstitution

1 reference

https://pubmed.ncbi.nlm.nih.gov/23418011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

COMPARATIVE STUDIES OF LIVER AND MUSCLE ALDOLASE. II. IMMUNOCHEMICAL AND CHROMATOGRAPHIC DIFFERENTIATION

1 reference

https://pubmed.ncbi.nlm.nih.gov/23418011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convergent synthesis of peptide conjugates using dehydroalanines for chemoselective ligations

1 reference

https://pubmed.ncbi.nlm.nih.gov/23418011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Buffers of constant ionic strength for studying pH-dependent processes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23418011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionization constants and stability constants of the copper(II)-complexes of some amino acids and their sulfur-containing analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/23418011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The formation of anhydrochymotrypsin by removing the elements of water from the serine at the active site

1 reference

https://pubmed.ncbi.nlm.nih.gov/23418011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of activity to catalytically deficient mutants of ribulosebisphosphate carboxylase/oxygenase by aminoethylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23418011

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/CBIC.201200714

0 references

0 references

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27676442&oldid=1458776371"