(Q27676531)

5

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Andrea Scozzafava

4

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Claudiu T Supuran

6

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author name string

Fabrizio Carta

1

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Mayank Aggarwal

2

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Alfonso Maresca

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

3

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language of work or name

English

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publication date

11 February 2012

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published in

Chemical Communications

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volume

48

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issue

13

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page(s)

1868-70

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cites work

1 reference

https://api.crossref.org/works/10.1039%2FC2CC16395K

Carbonic anhydrase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC16395K

Carbonic anhydrase inhibitors

21 January 2018

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Carbonic anhydrase inhibition/activation: trip of a scientist around the world in the search of novel chemotypes and drug targets

21 January 2018

1 reference

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Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors

21 January 2018

1 reference

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Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins

21 January 2018

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Interfering with pH regulation in tumours as a therapeutic strategy

21 January 2018

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Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies

21 January 2018

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Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule

21 January 2018

1 reference

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7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range

21 January 2018

1 reference

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Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II.

21 January 2018

1 reference

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Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency

21 January 2018

1 reference

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Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide

21 January 2018

1 reference

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Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors

21 January 2018

1 reference

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Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations

21 January 2018

1 reference

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Entrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase II

21 January 2018

1 reference

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Carbonic Anhydrase: Evolution of the Zinc Binding Site by Nature and by Design

21 January 2018

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Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste

21 January 2018

1 reference

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Refined structure of human carbonic anhydrase II at 2.0 A resolution

21 January 2018

1 reference

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Bidentate Zinc Chelators for α-Carbonic Anhydrases that Produce a Trigonal Bipyramidal Coordination Geometry

21 January 2018

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Low molecular weight compounds with transition metals as free radical scavengers and novel therapeutic agents

21 January 2018

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Environmental and pharmaceutical analysis of dithiocarbamates.

21 January 2018

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Potent inhibitory effects of benzyl and p-xylidine-bis dithiocarbamate sodium salts on activities of mushroom tyrosinase

21 January 2018

1 reference

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Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions

21 January 2018

1 reference

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Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC16395K

Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct--an inhibitor mimicking the sulfonamide and urea binding to the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC16395K

Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC16395K

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC16395K

N-Hydroxyurea—A versatile zinc binding function in the design of metalloenzyme inhibitors

21 January 2018

1 reference

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