(Q27676704)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge B2a of the ribosome (English)

1 reference

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20 January 2020

0 references

1

1 reference

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20 January 2020

author name string

Francis Johnson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Thomas A Steitz

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

2 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular Biology

20 January 2020

published in

1 reference

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20 January 2020

volume

416

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

571-578

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json

Structures of the bacterial ribosome in classical and hybrid states of tRNA binding

20 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Crystal structure of the eukaryotic ribosome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Revisiting the structures of several antibiotics bound to the bacterial ribosome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Structures of the ribosome in intermediate states of ratcheting

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

R chi-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Structural basis for hygromycin B inhibition of protein biosynthesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Analysis of the function of E. coli 23S rRNA helix-loop 69 by mutagenesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Crystal structure of an initiation factor bound to the 30S ribosomal subunit

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Phasercrystallographic software

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Structure of the 70S ribosome complexed with mRNA and tRNA

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Detection, delineation, measurement and display of cavities in macromolecular structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

A ratchet-like inter-subunit reorganization of the ribosome during translocation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Critical shortage of new antibiotics in development against multidrug-resistant bacteria-Time to react is now.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

The A-Z of bacterial translation inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Conserved loop sequence of helix 69 in Escherichia coli 23 S rRNA is involved in A-site tRNA binding and translational fidelity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Structure-based drug design meets the ribosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

The cryo-EM structure of a translation initiation complex from Escherichia coli

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Ribosomal localization of translation initiation factor IF2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Ribosomal intersubunit bridge B2a is involved in factor-dependent translation initiation and translational processivity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Deletion of a conserved, central ribosomal intersubunit RNA bridge

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Conformational transition of initiation factor 2 from the GTP- to GDP-bound state visualized on the ribosome.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

THERMORUBIN, A NEW ANTIBIOTIC FROM A THERMOACTINOMYCETE.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

The protein synthesis inhibitor thermorubin. 1. Nature of the thermorubin-ribosome complex.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3336878

Synthesis and antibacterial activity of some derivatives of the antibiotic thermorubin

27 November 2018

1 reference

12 December 2020

The protein synthesis inhibitor thermorubin. 2. Mechanism of inhibition of initiation on Escherichia coli ribosomes

1 reference

12 December 2020

Inhibition of peptide chain initiation in Escherichia coli by thermorubin

1 reference

12 December 2020

Pathogens Resistant to Antibacterial Agents

1 reference

12 December 2020

Thermorubin and 2-hydroxyphenyl acetic acid, aldose reductase inhibitors

1 reference

12 December 2020

10.1016/J.JMB.2011.12.055

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

22240456

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240456%20AND%20SRC:MED&resulttype=core&format=json