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The cryo-EM structure of a translation initiation complex from Escherichia coli

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Europe PubMed Central

2 August 2017

The cryo-EM structure of a translation initiation complex from Escherichia coli (English)

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Europe PubMed Central

2 August 2017

cryogenic electron microscopy

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Joachim Frank

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Andrey V. Zavialov

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Andrey Zavialov

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Måns Ehrenberg

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Måns Ehrenberg

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Europe PubMed Central

2 August 2017

Gregory S Allen

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Europe PubMed Central

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15935757

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2 August 2017

Richard Gursky

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Europe PubMed Central

PubMed ID

15935757

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English

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1 June 2005

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

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Europe PubMed Central

2 August 2017

5

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Europe PubMed Central

2 August 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

20 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1107/S0907444998003254

Mechanism of translational initiation in prokaryotes. IF3 is released from ribosomes during and not before 70 S initiation complex formation.

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11 October 2022

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Cross-linking of selected residues in the N- and C-terminal domains of Escherichia coli protein L7/L12 to other ribosomal proteins and the effect of elongation factor Tu.

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Effect of Escherichia coli initiation factors on the kinetics of N-AcPhe-tRNAPhe binding to 30S ribosomal subunits. A fluorescence stopped-flow study

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GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae

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Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset

1 reference

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Interaction of translation initiation factor 3 with the 30S ribosomal subunit

1 reference

11 October 2022

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Specific interaction of initiation factor IF2 of E. coli with formylmethionyl-tRNAfMet

1 reference

11 October 2022

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Binding of Escherichia coli initiation factor IF2 to 30S ribosomal subunits: a functional role for the N-terminus of the factor

1 reference

11 October 2022

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The guanine nucleotide-binding switch in three dimensions

1 reference

11 October 2022

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GTPase activation of elongation factors Tu and G on the ribosome

1 reference

11 October 2022

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Study of the interaction of Escherichia coli initiation factor IF2 with formylmethionyl-tRNAMetf by partial digestion with cobra venom ribonuclease

1 reference

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Inhibition by thiostrepton of the IF-2-dependent ribosomal GTPase

1 reference

11 October 2022

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Novel roles for classical factors at the interface between translation termination and initiation

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A ratchet-like inter-subunit reorganization of the ribosome during translocation

1 reference

11 October 2022

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Binding of initiation factor 2 and initiator tRNA to the Escherichia coli 30S ribosomal subunit induces allosteric transitions in 16S rRNA

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

From structure and dynamics of protein L7/L12 to molecular switching in ribosome

1 reference

11 October 2022

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Anticodon sequence mutants of Escherichia coli initiator tRNA: effects of overproduction of aminoacyl-tRNA synthetases, methionyl-tRNA formyltransferase, and initiation factor 2 on activity in initiation

1 reference

11 October 2022

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Light-scattering studies showing the effect of initiation factors on the reversible dissociation of Escherichia coli ribosomes

1 reference

11 October 2022

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SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

1 reference

11 October 2022

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The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites

1 reference

11 October 2022

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Fast 3D motif search of EM density maps using a locally normalized cross-correlation function

1 reference

11 October 2022

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Stability of macromolecular complexes

1 reference

11 October 2022

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Escherichia coli initiation factors: Isolation of an IF2-fMet-transfer RNA complex

1 reference

11 October 2022

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In vitro study of two dominant inhibitory GTPase mutants of Escherichia coli translation initiation factor IF2. Direct evidence that GTP hydrolysis is necessary for factor recycling

1 reference

11 October 2022

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Tandem translation of E. coli initiation factor IF2 beta: purification and characterization in vitro of two active forms.

1 reference

11 October 2022

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Binding of Escherichia coli protein synthesis initiation factor IF1 to 30S ribosomal subunits measured by fluorescence polarization.

1 reference

11 October 2022

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Initiation of mRNA translation in prokaryotes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

A complex between initiation factor IF2, guanosine triphosphate, and fMet-tRNA: an intermediate in initiation complex formation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Mechanism of translational initiation in prokaryotes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Uncoupling of initiation factor eIF5B/IF2 GTPase and translational activities by mutations that lower ribosome affinity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

X-Ray structures of the universal translation initiation factor IF2/eIF5B: conformational changes on GDP and GTP binding

1 reference

11 October 2022

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The crystal structure of yeast phenylalanine tRNA at 1.93 A resolution: a classic structure revisited

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Crystal structure of an initiation factor bound to the 30S ribosomal subunit

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Universal conservation in translation initiation revealed by human and archaeal homologs of bacterial translation initiation factor IF2

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

The mechanism of action of initiation factor IF1: Non-analogy with elongation factor EFTs

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Location of translational initiation factor IF3 on the small ribosomal subunit

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

MODBASE, a database of annotated comparative protein structure models, and associated resources.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Characterization of the domains of E. coli initiation factor IF2 responsible for recognition of the ribosome

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Peptidyl-tRNA regulates the GTPase activity of translation factors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Initiation factor dependent release of aminoacyl-tRNAs from complexes of 30S ribosomal subunits, synthetic polynucleotide and aminoacyl tRNA.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Locking and unlocking of ribosomal motions

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Mechanism of protein biosynthesis in prokaryotic cells. Effect of initiation factor IF1 on the initial rate of 30 S initiation complex formation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Cryo-electron microscopic localization of protein L7/L12 within the Escherichia coli 70 S ribosome by difference mapping and Nanogold labeling

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Ribosome formation from subunits studied by stopped-flow and rayleigh light scattering

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Low-resolution structure refinement in electron microscopy.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

11 October 2022

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The roles of initiation factor 2 and guanosine triphosphate in initiation of protein synthesis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Ribosomal localization of translation initiation factor IF2

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Mapping the fMet-tRNA(f)(Met) binding site of initiation factor IF2.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

tRNA selection and kinetic proofreading in translation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

A posttermination ribosomal complex is the guanine nucleotide exchange factor for peptide release factor RF3.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Domains of initiator tRNA and initiation codon crucial for initiator tRNA selection by Escherichia coli IF3

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Selection of the initiator tRNA by Escherichia coli initiation factors.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Cation-induced regulatory mechanism of GTPase activity dependent on polypeptide initiation factor 2

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

Study of the structural dynamics of the E coli 70S ribosome using real-space refinement

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.CELL.2005.03.023

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10.1016/J.CELL.2005.03.023

1 reference

stated in

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

PubMed ID

15935757

retrieved

2 August 2017

ResearchGate publication ID

7806077

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(Q34423776)

The cryo-EM structure of a translation initiation complex from Escherichia coli

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