(Q27676911)

1

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Terese Bergfors

2

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Torsten Unge

3

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Sherry L Mowbray

4

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T Alwyn Jones

Acta Crystallographica Section D: Biological Crystallography

5

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publication date

February 2012

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published in

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volume

68

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issue

Pt 2

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page(s)

134-43

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cites work

Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Synthesis and antiplasmodial activity of highly active reverse analogues of the antimalarial drug candidate fosmidomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Reverse fosmidomycin derivatives against the antimalarial drug target IspC (Dxr)

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Biochemistry of Polyisoprenoid Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Fosmidomycin-clindamycin for the treatment of Plasmodium falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Inhibition of 1-Deoxy- d -Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR, and Crystallographic Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

1-Deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis: towards understanding mycobacterial resistance to fosmidomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Accurate bond and angle parameters for X-ray protein structure refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Scaling and assessment of data quality

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

The MORPHEUS protein crystallization screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Synthesis of beta- and gamma-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Synthesis of alpha-substituted fosmidomycin analogues as highly potent Plasmodium falciparum growth inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Small revisions to predicted distances around metal sites in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Molray--a web interface between O and the POV-Ray ray tracer

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

The 1.9 A resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Phi/psi-chology: Ramachandran revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Clustal W and Clustal X version 2.0

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Fosmidomycin, a novel chemotherapeutic agent for malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

The integration of macromolecular diffraction data

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Solvent content of protein crystals

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Phasercrystallographic software

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

REFMAC5 for the refinement of macromolecular crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Novel deoxyxylulosephosphate-reductoisomerase inhibitors: fosmidomycin derivatives with spacious acyl residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Studies addressing the importance of charge in the binding of fosmidomycin-like molecules to deoxyxylulosephosphate reductoisomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Crystal structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase, a crucial enzyme in the non-mevalonate pathway of isoprenoid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase from the hyperthermophile Thermotoga maritima for insights into the coordination of conformational changes and an inhibitor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Synthesis and evaluation of alpha-halogenated analogues of 3-(acetylhydroxyamino)propylphosphonic acid (FR900098) as antimalarials

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Overview of the CCP4 suite and current developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Isoprenoid biosynthesis via the methylerythritol phosphate pathway: structural variations around phosphonate anchor and spacer of fosmidomycin, a potent inhibitor of deoxyxylulose phosphate reductoisomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231

Improved Fourier coefficients for maps using phases from partial structures with errors

21 January 2018

1 reference

https://api.crossref.org/works/10.1107%2FS0907444911052231