(Q27677668)

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Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES

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scholarly article

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Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES (English)

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crystal structure

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Mycobacterium tuberculosis

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3

object named as

Olivier Lequin

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object named as

Muriel Gondry

9

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Matthieu Fonvielle

object named as

Matthieu Fonvielle

1

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Marie-Hélène Le Du

2

object named as

Marie-Hélène Le Du

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author name string

Alain Lecoq

4

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Mickaël Jacquet

5

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Robert Thai

6

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Steven Dubois

7

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Guillaume Grach

8

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Pascal Belin

10

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language of work or name

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publication date

14 June 2013

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Journal of Biological Chemistry

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288

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24

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17347-59

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Application of fragment screening and merging to the discovery of inhibitors of the Mycobacterium tuberculosis cytochrome P450 CYP121

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20 March 2017

The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase

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20 March 2017

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682536

20 March 2017

Characterization of Active Site Structure in CYP121: A CYTOCHROME P450 ESSENTIAL FOR VIABILITY OF MYCOBACTERIUM TUBERCULOSIS H37Rv

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20 March 2017

Proton-coupled electron transfer

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20 March 2017

Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450

1 reference

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20 March 2017

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

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20 March 2017

The structural basis for substrate-induced changes in redox potential and spin equilibrium in cytochrome P-450CAM

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20 March 2017

Crystal structures of cytochrome P-450CAM complexed with camphane, thiocamphor, and adamantane: factors controlling P-450 substrate hydroxylation

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20 March 2017

Overview of the CCP4 suite and current developments

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20 March 2017

Features and development of Coot

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20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

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20 March 2017

Kinetics of ferric cytochrome P450 reduction by NADPH-cytochrome P450 reductase: rapid reduction in the absence of substrate and variations among cytochrome P450 systems

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20 March 2017

Cyclodipeptide synthases are a family of tRNA-dependent peptide bond-forming enzymes

1 reference

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20 March 2017

Expression, purification and spectroscopic characterization of the cytochrome P450 CYP121 from Mycobacterium tuberculosis

1 reference

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20 March 2017

Cytochrome P450 isozymes involved in the metabolism of phenol, a benzene metabolite

1 reference

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20 March 2017

The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways.

1 reference

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29 September 2017

Conformational plasticity and structure/function relationships in cytochromes P450.

1 reference

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29 September 2017

A medicinal chemist's guide to molecular interactions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682536

29 September 2017

The cytochrome p450 homepage.

1 reference

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29 September 2017

New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development

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29 September 2017

A predicted operon map for Mycobacterium tuberculosis

1 reference

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29 September 2017

Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis

1 reference

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29 September 2017

Structure and chemistry of cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682536

29 September 2017

Cytochrome P450: nature's most versatile biological catalyst

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682536

29 September 2017

Formation of formylkynurenine by the action of x-rays on tryptophan in aqueous solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682536

29 September 2017

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682536

29 September 2017

Photochemistry of proteins: a Review

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682536

29 September 2017

Benzene and phenol metabolism by mouse and rat liver microsomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682536

2 June 2018

The hydroxylation of tryptophan.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682536

2 June 2018

In vitro and ex vivo antimycobacterial potential of azole drugs against Mycobacterium tuberculosis H37Rv

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https://api.crossref.org/works/10.1074%2FJBC.M112.443853

21 January 2018

Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.443853

21 January 2018

Cyanohydridoborate anion as a selective reducing agent

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https://api.crossref.org/works/10.1074%2FJBC.M112.443853

21 January 2018

MOLREP: an Automated Program for Molecular Replacement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.443853

21 January 2018

Asymmetric Karplus curves for the protein side-chain 3J couplings.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.443853

21 January 2018

A proton-shuttle mechanism mediated by the porphyrin in benzene hydroxylation by cytochrome p450 enzymes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.443853

21 January 2018

Synthesis and biological activities of some pseudo-peptide analogs of tetragastrin: the importance of the peptide backbone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.443853

21 January 2018

Hydroxylation of phenol to catechol by Candida tropicalis: involvement of cytochrome P450.

1 reference

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27 November 2018

Oxidation of Free Tryptophan and Tryptophan Residues in Peptides and Proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of diastereoisomeric 3a-hydroxypyrroloindoles from a tryptophan residue analog mediated by iron (II)-EDTA and L-ascorbate

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploring privileged structures: the combinatorial synthesis of cyclic peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of ethanol-inducible P450 isozyme 3a (P450IIE1) as a benzene and phenol hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimycobacterial activity of econazole against multidrug-resistant strains of Mycobacterium tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformations of cyclic peptides. Folding of cyclic dipeptides containing an aromatic side chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isotopically labeled chlorobenzenes as probes for the mechanism of cytochrome P-450 catalyzed aromatic hydroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23620594

12 December 2020

based on heuristic

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Identifiers

10.1074/JBC.M112.443853

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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