(Q27678989)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Structure of a calcium-dependent 11R-lipoxygenase suggests a mechanism for Ca2+ regulation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Reet Järving

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Ivar Järving

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Nathaniel C Gilbert

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Marcia E Newcomer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Nigulas Samel

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

language of work or name

English

0 references

publication date

9 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

22377-22386

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

The structure of human 5-lipoxygenase

1 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

20 March 2017

1 reference

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The 1.85 Å Structure of an 8 R -Lipoxygenase Suggests a General Model for Lipoxygenase Product Specificity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Determination of protein structures--a series of fortunate events

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Conformational flexibility in mammalian 15S-lipoxygenase: Reinterpretation of the crystallographic data

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Multiple sequence alignment with the Clustal series of programs

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Characterisation of the calcium-binding C-terminal domain of Clostridium perfringens alpha-toxin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

A primary determinant for lipoxygenase positional specificity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Features and development of Coot

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Phasercrystallographic software

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Inference of macromolecular assemblies from crystalline state

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Protein production by auto-induction in high density shaking cultures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

UCSF Chimera--a visualization system for exploratory research and analysis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

ESPript: analysis of multiple sequence alignments in PostScript

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Reduced surface: an efficient way to compute molecular surfaces

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

The N-terminal β-barrel domain of mammalian lipoxygenases including mouse 5-lipoxygenase is not essential for catalytic activity and membrane binding but exhibits regulatory functions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Mechanisms of LDL oxidation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Molecular enzymology of lipoxygenases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Leukotriene pathway genetics and pharmacogenetics in allergy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Do human lipoxygenases have a PDZ regulatory domain?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Investigation of substrate binding and product stereochemistry issues in two linoleate 9-lipoxygenases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Lipoxygenase metabolism: roles in tumor progression and survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Control of oxygenation in lipoxygenase and cyclooxygenase catalysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Crystal structures of vegetative soybean lipoxygenase VLX-B and VLX-D, and comparisons with seed isoforms LOX-1 and LOX-3

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Structural biology of mammalian lipoxygenases: enzymatic consequences of targeted alterations of the protein structure.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

A comprehensive model of positional and stereo control in lipoxygenases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Structural organization of the regulatory domain of human 5-lipoxygenase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Applicability of the triad concept for the positional specificity of mammalian lipoxygenases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Structure-function properties of human platelet 12-lipoxygenase: chimeric enzyme and in vitro mutagenesis studies

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381197

Phenylalanine 353 is a primary determinant for the positional specificity of mammalian 15-lipoxygenases.

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Shape and specificity in mammalian 15-lipoxygenase active site. The functional interplay of sequence determinants for the reaction specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Defining the arachidonic acid binding site of human 15-lipoxygenase. Molecular modeling and mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Insights into the mechanism of binding of arachidonic acid to mammalian 15-lipoxygenases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Double dioxygenation by mouse 8S-lipoxygenase: specific formation of a potent peroxisome proliferator-activated receptor alpha agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via a C2-like domain and a structural basis of product chirality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Investigations into calcium-dependent membrane association of 15-lipoxygenase-1. Mechanistic roles of surface-exposed hydrophobic amino acids and calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Identification and characterization of an arachidonate 11R-lipoxygenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Tight association of N-terminal and catalytic subunits of rabbit 12/15-lipoxygenase is important for protein stability and catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Human platelet 12-lipoxygenase, new findings about its activity, membrane binding and low-resolution structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Identification of a naturally occurring peroxidase-lipoxygenase fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Identification of a functional allene oxide synthase-lipoxygenase fusion protein in the soft coral Gersemia fruticosa suggests the generality of this pathway in octocorals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Automated search-model discovery and preparation for structure solution by molecular replacement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2.0 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Steric control of oxygenation regiochemistry in soybean lipoxygenase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Kinetic Studies of Oxygen Reactivity in Soybean Lipoxygenase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

Probing Dimerization and Structural Flexibility of Mammalian Lipoxygenases by Small-Angle X-ray Scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.343285

The N-terminal domain of 5-lipoxygenase binds calcium and mediates calcium stimulation of enzyme activity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22573333

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Substrate binding to mammalian 15-lipoxygenase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22573333

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.343285

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

22573333

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22573333%20AND%20SRC:MED&resulttype=core&format=json