(Q27679174)

English

Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam

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scholarly article

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Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam (English)

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carbapenem antibiotic

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1 reference

based on heuristic

inferred from title

Robert A Bonomo

5

object named as

Robert A Bonomo

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object named as

Neil V Klinger

2

1 reference

ORCID Public Data File 2021

author name string

Kip-Chumba J Kaitany

1

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Cynthia M June

3

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Maddison E Ramey

4

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Rachel A Powers

6

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David A Leonard

7

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language of work or name

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publication date

October 2013

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Antimicrobial Agents and Chemotherapy

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57

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10

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4848-55

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Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D -lactamase OXA-10 by rational protein design

1 reference

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20 March 2017

Structures of the Class D Carbapenemase OXA-24 from Acinetobacter baumannii in Complex with Doripenem

1 reference

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20 March 2017

Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70

1 reference

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20 March 2017

Crystal Structure of the Narrow-Spectrum OXA-46 Class D -Lactamase: Relationship between Active-Site Lysine Carbamylation and Inhibition by Polycarboxylates

1 reference

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20 March 2017

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

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20 March 2017

The 1.4 Å Crystal Structure of the Class D β-Lactamase OXA-1 Complexed with Doripenem

1 reference

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20 March 2017

Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases

1 reference

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20 March 2017

Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases

1 reference

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20 March 2017

Genetic and Structural Characterization of an L201P Global Suppressor Substitution in TEM-1 β-Lactamase

1 reference

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20 March 2017

Crystal structure of the carbapenemase OXA-24 reveals insights into the mechanism of carbapenem hydrolysis

1 reference

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20 March 2017

Ultrahigh resolution structure of a class A beta-lactamase: on the mechanism and specificity of the extended-spectrum SHV-2 enzyme

1 reference

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20 March 2017

Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs

1 reference

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20 March 2017

Critical involvement of a carbamylated lysine in catalytic function of class D -lactamases

1 reference

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20 March 2017

Crystal structures of the class D beta-lactamase OXA-13 in the native form and in complex with meropenem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

20 March 2017

Crystal structure of the class D beta-lactamase OXA-10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

20 March 2017

Structure of the extended-spectrum class C beta-lactamase of Enterobacter cloacae GC1, a natural mutant with a tandem tripeptide insertion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

20 March 2017

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1 reference

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20 March 2017

Phasercrystallographic software

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

20 March 2017

Protein structure prediction on the Web: a case study using the Phyre server

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

20 March 2017

Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

20 March 2017

The CCP4 suite: programs for protein crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

20 March 2017

The rise of carbapenem-resistant Acinetobacter baumannii

1 reference

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29 September 2017

Inhibition of the class C beta-lactamase from Acinetobacter spp.: insights into effective inhibitor design

1 reference

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29 September 2017

Diversity, epidemiology, and genetics of class D beta-lactamases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

29 September 2017

Minor extended-spectrum beta-lactamases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

29 September 2017

Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center

1 reference

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29 September 2017

OXA-type carbapenemases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

29 September 2017

SHV-16, a beta-lactamase with a pentapeptide duplication in the omega loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

29 September 2017

OXA-24, a novel class D beta-lactamase with carbapenemase activity in an Acinetobacter baumannii clinical strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811470

29 September 2017

Selection and characterization of amino acid substitutions at residues 237-240 of TEM-1 beta-lactamase with altered substrate specificity for aztreonam and ceftazidime

1 reference

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29 September 2017

OXA-14, another extended-spectrum variant of OXA-10 (PSE-2) beta-lactamase from Pseudomonas aeruginosa

1 reference

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29 September 2017

Ceftazidime-hydrolysing β-lactamase OXA-145 with impaired hydrolysis of penicillins in Pseudomonas aeruginosa.

1 reference

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27 November 2018

OXA-163, an OXA-48-related class D β-lactamase with extended activity toward expanded-spectrum cephalosporins

1 reference

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27 November 2018

Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate.

1 reference

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27 November 2018

X-ray crystal structure of the acylated beta-lactam sensor domain of BlaR1 from Staphylococcus aureus and the mechanism of receptor activation for signal transduction

1 reference

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27 November 2018

Transferable imipenem-resistance in Acinetobacter species from a clinical source.

1 reference

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27 November 2018

Molecular evolution of a class C beta-lactamase extending its substrate specificity

1 reference

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27 November 2018

Laboratory mutants of OXA-10 beta-lactamase giving ceftazidime resistance in Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/23877677

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23877677

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based on heuristic

inferred from PubMed ID database lookup

Mutagenesis of amino acid residues in the SHV-1 beta-lactamase: the premier role of Gly238Ser in penicillin and cephalosporin resistance

1 reference

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based on heuristic

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Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/23877677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00762-13

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