(Q27681323)

English

Acyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine- Guanine-Xanthine Phosphoribosyltransferase

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scholarly article

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Acyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine- Guanine-Xanthine Phosphoribosyltransferase (English)

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clinical chemistry

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Plasmodium falciparum

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Vern L. Schramm

10

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Keith Z Hazleton

object named as

Keith Z Hazleton

1

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object named as

Keith Clinch

4

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8

object named as

Steve C Almo

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Maria B Cassera

3

object named as

Maria B Cassera

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author name string

Meng-Chiao Ho

2

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Douglas R Crump

5

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Irving Rosario

6

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Emilio F Merino

7

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Peter C Tyler

9

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publication date

22 June 2012

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Chemistry and Biology

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19

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6

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721-30

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Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model

1 reference

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20 March 2017

Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics

1 reference

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20 March 2017

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

1 reference

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20 March 2017

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

1 reference

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20 March 2017

Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition

1 reference

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20 March 2017

The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor

1 reference

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20 March 2017

The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor

1 reference

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20 March 2017

Coot: model-building tools for molecular graphics

1 reference

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20 March 2017

The CCP4 suite: programs for protein crystallography

1 reference

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20 March 2017

A graphical user interface to the CCP4 program suite

1 reference

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A FAMILIAL DISORDER OF URIC ACID METABOLISM AND CENTRAL NERVOUS SYSTEM FUNCTION

1 reference

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20 March 2017

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

1 reference

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7 April 2017

Plasmodium falciparum phospholipase C hydrolyzing sphingomyelin and lysocholinephospholipids is a possible target for malaria chemotherapy

1 reference

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24 May 2017

Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art.

1 reference

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29 September 2017

Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases

1 reference

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29 September 2017

Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

29 September 2017

Phosphoinositide metabolism and the morphology of human erythrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

29 September 2017

Enzyme Defect Associated with a Sex-Linked Human Neurological Disorder and Excessive Purine Synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

29 September 2017

A calcium-activated polyphosphoinositide phosphodiesterase in the plasma membrane of human and rabbit erythrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

29 September 2017

Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

2 June 2018

Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

2 June 2018

Neutral sphingomyelinase activity dependent on Mg2+ and anionic phospholipids in the intraerythrocytic malaria parasite Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

2 June 2018

An enzymatic basis for variation in response to allopurinol. Hypoxanthine-guanine phosphoribosyltransferase deficiency

1 reference

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2 June 2018

Hypoxanthine Depletion Induced by Xanthine Oxidase Inhibits Malaria Parasite Growth in Vitro

1 reference

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2 June 2018

Acyclic Ribooxacarbenium Ion Mimics as Transition State Analogues of Human and Malarial Purine Nucleoside Phosphorylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

27 November 2018

Steady-state kinetics of the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi

1 reference

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27 November 2018

Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases.

1 reference

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27 November 2018

Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase

1 reference

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27 November 2018

Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases

1 reference

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27 November 2018

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1 reference

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27 November 2018

Transition state structure of Salmonella typhimurium orotate phosphoribosyltransferase.

1 reference

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27 November 2018

Purine nucleoside phosphorylase. Catalytic mechanism and transition-state analysis of the arsenolysis reaction.

1 reference

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27 November 2018

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1 reference

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27 November 2018

Pre-steady-state transition-state analysis of the hydrolytic reaction catalyzed by purine nucleoside phosphorylase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

27 November 2018

Enzymes of purine and pyrimidine metabolism from the human malaria parasite, Plasmodium falciparum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397391

27 November 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/22726686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: rapid phosphoribosyl transfer chemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/22726686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CHEMBIOL.2012.04.012

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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