(Q27682746)

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Atomic Basis for the Species-specific Inhibition of V Integrins by Monoclonal Antibody 17E6 Is Revealed by the Crystal Structure of V 3 Ectodomain-17E6 Fab Complex

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Atomic basis for the species-specific inhibition of αV integrins by monoclonal antibody 17E6 is revealed by the crystal structure of αVβ3 ectodomain-17E6 Fab complex (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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crystal structure

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1 reference

based on heuristic

inferred from title

Simon L Goodman

11

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Europe PubMed Central

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12 March 2020

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Bhuvaneshwari Mahalingam

1

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12 March 2020

Johannes F Van Agthoven

2

1 reference

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12 March 2020

Jian-Ping Xiong

3

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12 March 2020

José Luis Alonso

4

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12 March 2020

Brian D Adair

5

1 reference

Europe PubMed Central

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12 March 2020

Xianliang Rui

6

1 reference

Europe PubMed Central

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12 March 2020

Saurabh Anand

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Mehrdad Mehrbod

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Mohammad R K Mofrad

9

1 reference

Europe PubMed Central

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12 March 2020

Christa Burger

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

M Amin Arnaout

12

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12 March 2020

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1 April 2014

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12 March 2020

Journal of Biological Chemistry

1 reference

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12 March 2020

289

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

20

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Europe PubMed Central

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12 March 2020

13801-13809

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

αV integrins in angiogenesis and cancer

1 reference

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20 March 2017

Molecular dynamics simulations of forced unbending of integrin α(v)β₃

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

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20 March 2017

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Crystal structure of the extracellular segment of integrin alpha Vbeta3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Scalable molecular dynamics with NAMD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Likelihood-enhanced fast rotation functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Integrins: bidirectional, allosteric signaling machines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

EMAN: semiautomated software for high-resolution single-particle reconstructions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Alpha v beta 1 is a receptor for vitronectin and fibrinogen, and acts with alpha 5 beta 1 to mediate spreading on fibronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

20 March 2017

Super-resolution biomolecular crystallography with low-resolution data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

7 April 2017

On the activation of integrin αIIbβ3: outside-in and inside-out pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Localized lipid packing of transmembrane domains impedes integrin clustering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

EM structure of the ectodomain of integrin CD11b/CD18 and localization of its ligand-binding site relative to the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Integrins as therapeutic targets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Activation of tumor cell integrin alphavbeta3 controls angiogenesis and metastatic growth in the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Mechanically activated integrin switch controls alpha5beta1 function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Integrin alpha IIb beta 3 in a membrane environment remains the same height after Mn2+ activation when observed by cryoelectron tomography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Structure and mechanics of integrin-based cell adhesion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Prostate cancer specific integrin alphavbeta3 modulates bone metastatic growth and tissue remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Three-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

Integrin activation and structural rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

29 September 2017

N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists

1 reference

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29 September 2017

Definition of an unexpected ligand recognition motif for alphav beta6 integrin

1 reference

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29 September 2017

Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3

1 reference

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29 September 2017

Identification of a novel integrin binding site in fibronectin. Differential utilization by beta 3 integrins

1 reference

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29 September 2017

An anti-alpha v-integrin antibody that blocks integrin function inhibits the development of a human melanoma in nude mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022854

2 June 2018

RGD peptides and monoclonal antibodies, antagonists of alpha(v)-integrin, enter the cells by independent endocytic pathways.

1 reference

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21 January 2018

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

1 reference

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21 January 2018

A fast SHAKE algorithm to solve distance constraint equations for small molecules in molecular dynamics simulations

1 reference

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21 January 2018

Molecular Basis of Ligand Recognition by Integrin α5β1

1 reference

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21 January 2018

Proton NMR assignment and secondary structure of the cell adhesion type III module of fibronectin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.546929

21 January 2018

Alpha v integrin antagonists induce the disassembly of focal contacts in melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24692540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid mutagenesis within ligand-binding loops in alpha v confers loss-of-function or gain-of-function phenotype on integrin alpha v beta 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/24692540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24692540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/24692540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical analysis of integrin alpha vbeta3 expression on tumor-associated vessels of human carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/24692540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.546929

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692540%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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