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Missing Fragments: Detecting Cooperative Binding in Fragment-Based Drug Design

scientific article published on 12 April 2012

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Missing Fragments: Detecting Cooperative Binding in Fragment-Based Drug Design (English)

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Nyssa Drinkwater

3

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Pramod C. Nair

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Pramod C Nair

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1

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Alpeshkumar K Malde

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Alpeshkumar K Malde

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2

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Alan Mark

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Alan E Mark

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4

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publication date

12 April 2012

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published in

ACS Medicinal Chemistry Letters

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volume

3

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issue

4

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page(s)

322-6

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cites work

Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

20 March 2017

Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

20 March 2017

Recent developments in fragment-based drug discovery

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

20 March 2017

Identification of 4-(4-aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as selective inhibitors of protein kinase B through fragment elaboration

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

20 March 2017

Discovery of a novel warhead against beta-secretase through fragment-based lead generation

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

20 March 2017

Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

20 March 2017

A biomolecular force field based on the free enthalpy of hydration and solvation: the GROMOS force-field parameter sets 53A5 and 53A6

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

7 April 2017

Using Theory to Reconcile Experiment: The Structural and Thermodynamic Basis of Ligand Recognition by Phenylethanolamine N-Methyltransferase (PNMT).

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

29 September 2017

Fragment-based lead discovery: challenges and opportunities

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

29 September 2017

The rise of fragment-based drug discovery

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

29 September 2017

Recent progress in fragment-based lead discovery

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

29 September 2017

From fragment to clinical candidate--a historical perspective.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

29 September 2017

Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

29 September 2017

The GROMOS software for biomolecular simulation: GROMOS05.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

29 September 2017

An Automated Force Field Topology Builder (ATB) and Repository: Version 1.0

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4025746

retrieved

27 November 2018

Challenges in the determination of the binding modes of non-standard ligands in X-ray crystal complexes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/24900472

retrieved

12 December 2020

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PubMed publication ID

24900472

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ResearchGate publication ID

262886459

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(Q27684142)

Missing Fragments: Detecting Cooperative Binding in Fragment-Based Drug Design

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