(Q27684187)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

0 references

0 references

1 reference

1

1 reference

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20 March 2020

2

Deepak Bandyopadhyay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

author name string

Scott B Berger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Nino Campobasso

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Carol A Capriotti

5

1 reference

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20 March 2020

Julie A Cox

6

1 reference

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20 March 2020

Lauren Dare

7

1 reference

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20 March 2020

Joshua N Finger

8

1 reference

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20 March 2020

Sandra J Hoffman

9

1 reference

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20 March 2020

Kirsten M Kahler

10

1 reference

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20 March 2020

Ruth Lehr

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

John D Lich

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Rakesh Nagilla

13

1 reference

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20 March 2020

Robert T Nolte

14

1 reference

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20 March 2020

Michael T Ouellette

15

1 reference

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20 March 2020

Christina S Pao

16

1 reference

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20 March 2020

Michelle C Schaeffer

17

1 reference

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20 March 2020

Angela Smallwood

18

1 reference

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20 March 2020

Helen H Sun

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Barbara A Swift

20

1 reference

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20 March 2020

Rachel D Totoritis

21

1 reference

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20 March 2020

Paris Ward

22

1 reference

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20 March 2020

Robert W Marquis

23

1 reference

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20 March 2020

John Bertin

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Peter J Gough

25

1 reference

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20 March 2020

publication date

4 November 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

ACS Medicinal Chemistry Letters

20 March 2020

published in

2 references

Crossref

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

volume

4

1 reference

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20 March 2020

page(s)

1238-1243

1 reference

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20 March 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

Structural basis of RIP1 inhibition by necrostatins

20 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

DAMPs, PAMPs and alarmins: all we need to know about danger

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Comprehensive analysis of kinase inhibitor selectivity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Identification of RIP1 kinase as a specific cellular target of necrostatins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Rational design of inhibitors that bind to inactive kinase conformations

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Synergistic protective effects of humanin and necrostatin-1 on hypoxia and ischemia/reperfusion injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Type-II kinase inhibitor docking, screening, and profiling using modified structures of active kinase states

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Necrostatin: a potentially novel cardioprotective agent?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Necroptosis turns TNF lethal

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027519

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900635

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Orally active 4-amino-5-diarylurea-furo[2,3-d]pyrimidine derivatives as anti-angiogenic agent inhibiting VEGFR2 and Tie-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900635

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML400382P

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24900635%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference