(Q27684726)

1

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Alyssa D Lokits

2

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James A Gilbert

3

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Tina M Iverson

4

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Heidi E Hamm

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

29 August 2014

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published in

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volume

289

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issue

35

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page(s)

24475-87

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cites work

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Structural evidence for a sequential release mechanism for activation of heterotrimeric G proteins

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Helix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in Gα i Subunits † , ‡

20 March 2017

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Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography.

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20 March 2017

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Crystal structures of the G protein Gi alpha 1 complexed with GDP and Mg2+: a crystallographic titration experiment

20 March 2017

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The A326S mutant of Gialpha1 as an approximation of the receptor-bound state

20 March 2017

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Lipid modifications of G proteins: alpha subunits are palmitoylated

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Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

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20 March 2017

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Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

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Coot: model-building tools for molecular graphics

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A graphical user interface to the CCP4 program suite

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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GDP release preferentially occurs on the phosphate side in heterotrimeric G-proteins

20 March 2017

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The many faces of G protein signaling

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

20 March 2017

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The structure and function of G-protein-coupled receptors

7 April 2017

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G protein mechanisms: insights from structural analysis

7 April 2017

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Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release

7 April 2017

1 reference

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Allosteric mechanisms of G protein-Coupled Receptor signaling: a structural perspective

29 September 2017

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Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex

29 September 2017

1 reference

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Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit

29 September 2017

1 reference

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A sweet cycle for Arabidopsis G-proteins: Recent discoveries and controversies in plant G-protein signal transduction

29 September 2017

1 reference

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How do receptors activate G proteins?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features

29 September 2017

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Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

Structural basis of function in heterotrimeric G proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

Mutant G protein alpha subunit activated by Gbeta gamma: a model for receptor activation?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

Biological and structural characterization of a Ras transforming mutation at the phenylalanine-156 residue, which is conserved in all members of the Ras superfamily

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

Structural analysis of rod GTP-binding protein, Gt. Limited proteolytic digestion pattern of Gt with four proteases defines monoclonal antibody epitope

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

The function of interdomain interactions in controlling nucleotide exchange rates in transducin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

G-protein diseases furnish a model for the turn-on switch

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

How receptors talk to trimeric G proteins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

Specificity of G protein beta and gamma subunit interactions.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4148873

Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572875

Intrinsic biophysical monitors of transducin activation: fluorescence, UV-visible spectroscopy, light scattering, and evanescent field techniques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572875

Rapid activation of transducin by mutations distant from the nucleotide-binding site: evidence for a mechanistic model of receptor-catalyzed nucleotide exchange by G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572875

Disruption of the alpha5 helix of transducin impairs rhodopsin-catalyzed nucleotide exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572875

Heterotrimeric G-protein alpha-subunit adopts a "preactivated" conformation when associated with betagamma-subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572875

Molecular dynamics simulations of transducin: interdomain and front to back communication in activation and nucleotide exchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572875

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572875

Biochemical and functional characterization of germ line KRAS mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.572875

Site of G protein binding to rhodopsin mapped with synthetic peptides from the alpha subunit

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25037222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of G-protein Galpha subunits by receptors through Galpha-Gbeta and Galpha-Ggamma interactions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25037222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.572875

1 reference

3228880

3228880

1 reference

1 reference

1 reference