(Q27687620)

3

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author name string

Jeremy Murray

1

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Anthony M Giannetti

2

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Paul Gibbons

4

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Brian R Hearn

5

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Frederick Cohen

6

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Christine Tam

7

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Christine Pozniak

8

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Brandon Bravo

9

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Joe Lewcock

10

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Priyadarshini Jaishankar

11

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Cuong Q Ly

12

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Xianrui Zhao

13

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Yinyan Tang

14

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Preeti Chugha

15

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Michelle R Arkin

16

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John Flygare

17

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Adam R Renslo

Caspases in cell survival, proliferation and differentiation.

18

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publication date

January 2014

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published in

ChemMedChem

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volume

9

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page(s)

73-7, 2

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issue

1

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cites work

1 reference

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The apoptosome: signalling platform of cell death

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Caspase substrates and cellular remodeling

21 January 2018

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Discovery of an allosteric site in the caspases

21 January 2018

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A common allosteric site and mechanism in caspases

21 January 2018

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Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy

21 January 2018

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Small-molecule activators of a proenzyme

21 January 2018

1 reference

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Allosteric peptides bind a caspase zymogen and mediate caspase tetramerization

21 January 2018

1 reference

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Structural biology in fragment-based drug design

21 January 2018

1 reference

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Fragment-based approaches in drug discovery and chemical biology

21 January 2018

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Combining biophysical screening and X-ray crystallography for fragment-based drug discovery

21 January 2018

1 reference

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Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300424

From experimental design to validated hits a comprehensive walk-through of fragment lead identification using surface plasmon resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300424

Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6

21 January 2018

1 reference

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Orthogonal multipolar interactions in structural chemistry and biology

21 January 2018

1 reference

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Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series TargetingMycobacterium tuberculosisCYP121

21 January 2018

1 reference

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Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination

21 January 2018

1 reference

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