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Chemically modified non-antimicrobial tetracyclines are multifunctional drugs against advanced cancers
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scholarly article
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stated in
PubMed
title
Chemically modified non-antimicrobial tetracyclines are multifunctional drugs against advanced cancers
(English)
1 reference
stated in
PubMed
main subject
tetracycline
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based on heuristic
inferred from title
author name string
Bal L. Lokeshwar
series ordinal
1
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stated in
Crossref
publication date
February 2011
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stated in
PubMed
published in
Pharmacological Research
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stated in
PubMed
volume
63
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PubMed
issue
2
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PubMed
page(s)
146-50
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PubMed
cites work
Cancer statistics, 2010
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
20 March 2017
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
20 March 2017
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
20 March 2017
Matrix metalloproteinases: regulators of the tumor microenvironment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
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7 April 2017
Early prostate-specific antigen changes and the diagnosis and prognosis of prostate cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
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29 September 2017
Diagnostic evaluation of PSA recurrence and review of hormonal management after radical prostatectomy.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
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29 September 2017
Proteases, growth factors, chemokines, and the microenvironment in prostate cancer bone metastasis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
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29 September 2017
Effect of zoledronic acid on the doxycycline-induced decrease in tumour burden in a bone metastasis model of human breast cancer.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
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29 September 2017
Tetracycline analogues (doxycycline and COL-3) induce caspase-dependent and -independent apoptosis in human colon cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Inhibition of cyclooxygenase (COX)-2 expression by Tet-inducible COX-2 antisense cDNA in hormone-refractory prostate cancer significantly slows tumor growth and improves efficacy of chemotherapeutic drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Mechanisms of bone metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Doxycycline and other tetracyclines in the treatment of bone metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Doxycycline decreases tumor burden in a bone metastasis model of human breast cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Cytotoxic activity and inhibition of tumor cell invasion by derivatives of a chemically modified tetracycline CMT-3 (COL-3).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Establishment of human prostate carcinoma skeletal metastasis models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Severe combined immunodeficient-hu model of human prostate cancer metastasis to human bone.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Use of tetracycline as an inhibitor of matrix metalloproteinase activity secreted by human bone-metastasizing cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Inhibition of proliferation and induction of apoptosis by doxycycline in cultured human osteosarcoma cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
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29 September 2017
Metastatic prostate cancer in a transgenic mouse
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
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29 September 2017
Autocrine factors, type IV collagenase secretion and prostatic cancer cell invasion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Modulation of bone resorption by tetracyclines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Effects of doxycycline on in vitro growth, migration, and gelatinase activity of breast carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Prostate Specific Antigen: A Critical Assessment of the Most Useful Tumor Marker for Adenocarcinoma of the Prostate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
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29 September 2017
The metastatic spread of kidney and prostate cancers in man
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
29 September 2017
Establishment and characterization of seven Dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
2 June 2018
Development of skeletal metastasis by human prostate cancer in athymic nude mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
2 June 2018
Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
27 November 2018
Targeting the tumor microenvironment with chemically modified tetracyclines: inhibition of laminin 5 gamma2 chain promigratory fragments and vasculogenic mimicry.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
27 November 2018
Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non-antimicrobial tetracycline analog (COL-3) in a metastatic prostate cancer model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
27 November 2018
Matrix metalloproteinase activity, bone matrix turnover, and tumor cell proliferation in prostate cancer bone metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031750
retrieved
27 November 2018
Differential regulation of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 (TIMP-1) and TIMP-2 expression in co-cultures of prostate cancer and stromal cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Establishment and characterization of osseous prostate cancer models: intra-tibial injection of human prostate cancer cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Minocycline reduces gingival collagenolytic activity during diabetes. Preliminary observations and a proposed new mechanism of action
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Tetracyclines inhibit tissue collagenase activity. A new mechanism in the treatment of periodontal disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Prostatic tumor (R3327) skeletal metastasis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Type IV collagenase (M(r) 72,000) expression in human prostate: benign and malignant tissue
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Secretion of matrix metalloproteinases and their inhibitors (tissue inhibitor of metalloproteinases) by human prostate in explant cultures: reduced tissue inhibitor of metalloproteinase secretion by malignant tissues
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Bone cells and matrix bind chemically modified non-antimicrobial tetracycline
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effects of doxycycline on cancer cells in vitro and in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Potential application of a chemically modified non-antimicrobial tetracycline (CMT-3) against metastatic prostate cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interaction between stromal cells and tumor cells induces chemoresistance and matrix metalloproteinase secretion
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
CMT-3, a chemically modified tetracycline, inhibits bony metastases and delays the development of paraplegia in a rat model of prostate cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21093590
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.PHRS.2010.11.003
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2824543
OpenCitations bibliographic resource ID
2824543
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2824543
PMCID
3031750
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2824543
PubMed ID
21093590
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2824543
ResearchGate publication ID
49624832
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