(Q27704919)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

4

1 reference

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2 April 2020

Andrea Cochran

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Matthew J Wongchenko

18

1 reference

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2 April 2020

James R Kiefer

33

1 reference

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2 April 2020

34

Patrick Trojer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

author name string

Maia Vinogradova

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Victor S Gehling

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Amy Gustafson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Charles A Tindell

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Catherine Wilson

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Kaylyn E Williamson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Gulfem D Guler

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Pranoti Gangurde

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Wanda Manieri

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Jennifer Busby

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

E Megan Flynn

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Fei Lan

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Hyo-Jin Kim

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Shobu Odate

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Yichin Liu

17

1 reference

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2 April 2020

Yibin Yang

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Tommy K Cheung

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Tobias M Maile

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Ted Lau

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Michael Costa

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Ganapati V Hegde

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Erica Jackson

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Robert Pitti

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

David Arnott

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Christopher Bailey

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Steve Bellon

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Richard T Cummings

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Brian K Albrecht

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Marie Classon

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Jean-Christophe Harmange

32

1 reference

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2 April 2020

publication date

23 May 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

page(s)

531-538

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27214401%20AND%20SRC:MED&resulttype=core&format=json

Histone methylation: a dynamic mark in health, disease and inheritance

2 April 2020

cites work

1 reference

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Mutational landscape and significance across 12 major cancer types

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Discovery and saturation analysis of cancer genes across 21 tumour types

21 April 2017

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Inhibition of 2-oxoglutarate dependent oxygenases

21 April 2017

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Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway

21 April 2017

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Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

21 April 2017

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Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A

21 April 2017

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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

21 April 2017

1 reference

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RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.2085

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

21 April 2017

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Identifying and quantifying in vivo methylation sites by heavy methyl SILAC

21 April 2017

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Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells

21 April 2017

1 reference

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The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif

21 April 2017

1 reference

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The structure of the Dead ringer-DNA complex reveals how AT-rich interaction domains (ARIDs) recognize DNA.

21 April 2017

1 reference

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Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

21 April 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 April 2017

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Coot: model-building tools for molecular graphics

21 April 2017

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A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

21 April 2017

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.2085

JmjC-domain-containing proteins and histone demethylation

21 April 2017

1 reference

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Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap

21 April 2017

1 reference

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Targeting histone lysine methylation in cancer

21 April 2017

1 reference

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The mutational landscape of chromatin regulatory factors across 4,623 tumor samples

21 January 2018

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Pan-cancer patterns of somatic copy number alteration

21 January 2018

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SET for life: biochemical activities and biological functions of SET domain-containing proteins

21 January 2018

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Molecular mechanisms and potential functions of histone demethylases

21 January 2018

1 reference

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Coordinated methyl-lysine erasure: structural and functional linkage of a Jumonji demethylase domain and a reader domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2085

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2085

PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation

21 January 2018

1 reference

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Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2085

Structural insights into histone demethylation by JMJD2 family members.

21 January 2018

1 reference

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Targeting histone lysine demethylases - progress, challenges, and the future

21 January 2018

1 reference

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Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.

21 January 2018

1 reference

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Inhibition of demethylases by GSK-J1/J4.

21 January 2018

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The retinoblastoma binding protein RBP2 is an H3K4 demethylase

21 January 2018

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Demethylation of trimethylated histone H3 Lys4 in vivo by JARID1 JmjC proteins.

21 January 2018

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A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

21 January 2018

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The cancer stem cell marker aldehyde dehydrogenase is required to maintain a drug-tolerant tumor cell subpopulation

21 January 2018

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Identification of EZH2 and EZH1 small molecule inhibitors with selective impact on diffuse large B cell lymphoma cell growth

21 January 2018

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Mass spectrometric quantification of histone post-translational modifications by a hybrid chemical labeling method

21 January 2018

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21 January 2018

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Chemical derivatization of histones for facilitated analysis by mass spectrometry.

21 January 2018

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21 January 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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The KDM5 family of histone demethylases as targets in oncology drug discovery

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27214401

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27214401

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular mechanisms and potential functions of histone demethylases

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2085