(Q27739531)

1

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I J Clifton

2

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C M Hensgens

3

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C J Schofield

5

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J Hajdu

6

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J E Baldwin

The biosynthesis of penicillins and cephalosporins

7

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language of work or name

English

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publication date

19 June 1997

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published in

Nature

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volume

387

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page(s)

827-30

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issue

6635

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cites work

1 reference

Purification of isopenicillin N synthetase

21 January 2018

1 reference

Dioxygen Activation by Enzymes with Mononuclear Non-Heme Iron Active Sites

21 January 2018

1 reference

Thiolate ligation of the active site Fe2+ of isopenicillin N synthase derives from substrate rather than endogenous cysteine: spectroscopic studies of site-specific Cys----Ser mutated enzymes

21 January 2018

1 reference

Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes

21 January 2018

1 reference

Ferrous active site of isopenicillin N synthase: genetic and sequence analysis of the endogenous ligands

21 January 2018

1 reference

The enzymes involved in biosynthesis of penicillin and cephalosporin; their structure and function

21 January 2018

1 reference

A stereochemical concept for the catalytic mechanism of prolylhydroxylase: applicability to classification and design of inhibitors.

21 January 2018

1 reference

Crystal structure of the biphenyl-cleaving extradiol dioxygenase from a PCB-degrading pseudomonad

21 January 2018

1 reference

Three-dimensional structures of free form and two substrate complexes of an extradiol ring-cleavage type dioxygenase, the BphC enzyme from Pseudomonas sp. strain KKS102

21 January 2018

1 reference

AMoRe: an automated package for molecular replacement

21 January 2018

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

Crystallographic R factor refinement by molecular dynamics

21 January 2018

1 reference

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

X-ray absorption studies of the ferrous active site of isopenicillin N synthase and related model complexes

21 January 2018

1 reference

Anaerobic Crystallisation of an Isopenicillin N Synthase . Fe(II) . Substrate Complex Demonstrated by X-Ray Studies

21 January 2018

1 reference

Electron transport in cytochromes P-450 by covalent switching

21 January 2018

1 reference

X-ray absorption spectroscopic studies of the Fe(II) active site of catechol 2,3-dioxygenase. Implications for the extradiol cleavage mechanism

21 January 2018

1 reference

Penicillin biosynthesis: active site mapping with aminoadipoylcysteinylvaline variants

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis; 2. Incubation and interpretation

1 reference