(Q27743588)

English

The NMR solution conformation of unligated human cyclophilin A

scientific article

In more languages

edit

Statements

instance of

scholarly article

0 references

title

The NMR solution conformation of unligated human cyclophilin A (English)

0 references

author

Kurt Wüthrich

series ordinal

4

0 references

author name string

M Ottiger

series ordinal

1

0 references

O Zerbe

series ordinal

2

0 references

P Güntert

series ordinal

3

0 references

language of work or name

English

0 references

publication date

12 September 1997

0 references

published in

Journal of Molecular Biology

0 references

volume

272

0 references

issue

1

0 references

page(s)

64-81

0 references

cites work

Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

The Molecular Replacement Solution and X-ray Refinement to 2.8 Å of a Decameric Complex of Human Cyclophilin A with the Immunosuppressive Drug Cyclosporin A

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Correlating backbone amide and side chain resonances in larger proteins by multiple relayed triple resonance NMR

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Functional association of cyclophilin A with HIV-1 virions

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Heteronuclear filters in two-dimensional [1H,1H]-NMR spectroscopy: combined use with isotope labelling for studies of macromolecular conformation and intermolecular interactions

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Amino acid type determination in the sequential assignment procedure of uniformly 13C/15N-enriched proteins.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

NMR studies of [U-13C]cyclosporin A bound to cyclophilin: bound conformation and portions of cyclosporin involved in binding

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolution

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Protein folding by restrained energy minimization and molecular dynamics

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional 13C labeling

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Protein dynamics studied by rotating frame 15N spin relaxation times.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Improved efficiency of protein structure calculations from NMR data using the program DIANA with redundant dihedral angle constraints.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

The substrate-binding site in Escherichia coli cyclophilin A preferably recognizes a cis-proline isomer or a highly distorted form of the trans isomer

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Protein structure comparison by alignment of distance matrices

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

MOLMOL: a program for display and analysis of macromolecular structures

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

The NMR structure of cyclosporin A bound to cyclophilin in aqueous solution

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Conformational polymorphism of cyclosporin A

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

The X-ray structure of a tetrapeptide bound to the active site of human cyclophilin A

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

X-ray structure of a cyclophilin B/cyclosporin complex: comparison with cyclophilin A and delineation of its calcineurin-binding domain

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Polypeptide secondary structure determination by nuclear magnetic resonance observation of short proton-proton distances

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Investigation of protein motions via relaxation measurements

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Pseudo-structures for the 20 common amino acids for use in studies of protein conformations by measurements of intramolecular proton-proton distance constraints with nuclear magnetic resonance

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Crystal structure implies that cyclophilin predominantly catalyzes the trans to cis isomerization

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Complete 1H, 13C and 15N NMR assignments and secondary structure of the 269-residue serine protease PB92 from Bacillus alcalophilus

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Determination of the NMR solution structure of the cyclophilin A-cyclosporin A complex

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

The X-ray structure of (MeBm2t)1-cyclosporin complexed with cyclophilin A provides an explanation for its anomalously high immunosuppressive activity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Improved three-dimensional1H−13C−1H correlation spectroscopy of a13C-labeled protein using constant-time evolution

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Ring current effects in the conformation dependent NMR chemical shifts of aliphatic protons in the basic pancreatic trypsin inhibitor

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

A Simple Experimental Scheme Using Pulsed Field Gradients for Coherence-Pathway Rejection and Solvent Suppression in Phase-Sensitive Heteronuclear Correlation Spectra

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

15N NMR relaxation studies of the FK506 binding protein: dynamic effects of ligand binding and implications for calcineurin recognition

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

The new program OPAL for molecular dynamics simulations and energy refinements of biological macromolecules

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Three-dimensional solution structure of Escherichia coli periplasmic cyclophilin

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Resonance assignment of methionine methyl groups and chi 3 angular information from long-range proton-carbon and carbon-carbon J correlation in a calmodulin-peptide complex

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Processing of multi-dimensional NMR data with the new software PROSA

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Specific incorporation of cyclophilin A into HIV-1 virions

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Three-dimensional (1)H-TOCSY-relayed ct-[(13)C, (1)H]-HMQC for aromatic spin system identification in uniformly (13)C-labeled proteins

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Crystal structure of murine cyclophilin C complexed with immunosuppressive drug cyclosporin A

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

The role of water molecules in the structure-based design of (5-hydroxynorvaline)-2-cyclosporin: synthesis, biological activity, and crystallographic analysis with cyclophilin A

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Improved binding affinity for cyclophilin A by a cyclosporin derivative singly modified at its effector domain

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Crystal structure of cyclophilin A complexed with substrate Ala-Pro suggests a solvent-assisted mechanism of cis-trans isomerization

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

15N NMR relaxation studies of the FK506 binding protein: backbone dynamics of the uncomplexed receptor

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Efficient computation of three-dimensional protein structures in solution from nuclear magnetic resonance data using the program DIANA and the supporting programs CALIBA, HABAS and GLOMSA

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Receptor-induced conformation change of the immunosuppressant cyclosporin A.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Protein secondary structure determination by NMR. Application with recombinant human cyclophilin.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Cyclosporin A-cyclophilin complex formation. A model based on X-ray and NMR data

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Solution structure of the cyclosporin A/cyclophilin complex by NMR

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

An all atom force field for simulations of proteins and nucleic acids

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

IFLAT—A New Automatic Baseline-Correction Method for Multidimensional NMR Spectra with Strong Solvent Signals

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Proton-proton correlation via carbon-carbon couplings: a three-dimensional NMR approach for the assignment of aliphatic resonances in proteins labeled with carbon-13

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1997.1220

Identifiers

DOI

10.1006/JMBI.1997.1220

0 references

PubMed publication ID

9299338

0 references

ResearchGate publication ID

13922675

0 references

(Q27743588)

The NMR solution conformation of unligated human cyclophilin A

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)