(Q30195613)

10 June 2017

title

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy (English)

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10 June 2017

main subject

X-ray crystallography

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6

Wüthrich K

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10 June 2017

Kallen J

1

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10 June 2017

Spitzfaden C

2

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10 June 2017

Zurini MG

3

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10 June 2017

Wider G

4

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10 June 2017

Widmer H

5

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10 June 2017

Walkinshaw MD

7

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10 June 2017

language of work or name

English

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publication date

1 September 1991

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10 June 2017

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10 June 2017

volume

353

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10 June 2017

issue

6341

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10 June 2017

page(s)

276-279

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Cyclophilin: a specific cytosolic binding protein for cyclosporin A

10 June 2017

cites work

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7 January 2021

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

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7 January 2021

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

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7 January 2021

The NMR structure of cyclosporin A bound to cyclophilin in aqueous solution

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7 January 2021

NMR studies of [U-13C]cyclosporin A bound to cyclophilin: bound conformation and portions of cyclosporin involved in binding

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7 January 2021

Crystallisation and preliminary X-ray diffraction studies of cyclophilin-tetrapeptide and cyclophilin-cyclosporin complexes

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7 January 2021

Crystallographic refinement of human serum retinol binding protein at 2A resolution

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7 January 2021

Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis

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7 January 2021

Human and Escherichia coli cyclophilins: sensitivity to inhibition by the immunosuppressant cyclosporin A correlates with a specific tryptophan residue.

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7 January 2021

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

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7 January 2021

Solution Structure of FKBP, a Rotamase Enzyme and Receptor for FK506 and Rapamycin

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7 January 2021

Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex

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7 January 2021

Solution structure of the major binding protein for the immunosuppressant FK506

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7 January 2021

Sensitivity to cyclosporin A is mediated by cyclophilin in Neurospora crassa and Saccharomyces cerevisiae.

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7 January 2021

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

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7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

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7 January 2021

Crystallographic R factor refinement by molecular dynamics

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7 January 2021

Identifiers

DOI

10.1038/353276A0

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Dimensions Publication ID

10 June 2017

1009665506

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