(Q27749608)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

2

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11 November 2019

author name string

E Conti

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

A Wonacott

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

P Brick

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

language of work or name

English

0 references

publication date

1 March 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

number of pages

5

1 reference

based on heuristic

inferred from page(s)

published in

FEBS Letters

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

425

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

229-233

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

The structure of a complex of recombinant hirudin and human alpha-thrombin

11 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

The interaction of thrombin with fibrinogen. A structural basis for its specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

The binding of proflavin to thrombin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

The optical detection of transients in trypsin- and chymotrypsin-catalyzed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

Physical evidence for an apolar binding site near the catalytic center of human α-thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

A novel one-step purification of human α-thrombin after direct activation of crude prothrombin enriched from plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

Crystallographic R factor refinement by molecular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

A graphics model building and refinement system for macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. II. Crystallographic refinement, calcium binding site, benzamidine binding site and active site at pH 7.0

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

On the size of the active site in proteases. I. Papain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

On the interaction of the active side of alpha-chymotrypsin with chromophores: proflavin binding and enzyme conformation during catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

Proflavin binding within the fibrinopeptide groove adjacent to the catalytic site of human alpha-thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

Converting trypsin to chymotrypsin: ground-state binding does not determine substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

Activation of prothrombin with (taipan snake) venom

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

Are the structure and function of an enzyme the same in aqueous solution and in the wet crystal?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

Thermodynamics of substrates and reversible inhibitors binding to the active site cleft of human alpha-thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900235-X

10.1016/S0014-5793(98)00235-X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9559654%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference