(Q27759564)

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Molecular basis of phenotypic heterogeneity in phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Severity of mutation in the phenylalanine hydroxylase gene influences phenylalanine metabolism in phenylketonuria and hyperphenylalaninaemia heterozygotes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Structure and function of the aromatic amino acid hydroxylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Crystal structure of tyrosine hydroxylase at 2.3 A and its implications for inherited neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Homology between phenylalanine and tyrosine hydroxylases reveals common structural and functional domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Expression and characterization of catalytic and regulatory domains of rat tyrosine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Crystallization and preliminary X-ray analysis of phenylalanine hydroxylase from rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Crystallization and preliminary diffraction analysis of a truncated homodimer of human phenylalanine hydroxylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Regulation and crystallization of phosphorylated and dephosphorylated forms of truncated dimeric phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Expression and characterization of the catalytic domain of human phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

AMoRe: an automated package for molecular replacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Identification of metal ligands in Cu(II)-inhibited Chromobacterium violaceum phenylalanine hydroxylase by electron spin echo envelope modulation analysis of histidine to serine mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Identification of iron ligands in tyrosine hydroxylase by mutagenesis of conserved histidinyl residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

3D domain swapping: a mechanism for oligomer assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Spectroscopic and kinetic properties of unphosphorylated rat hepatic phenylalanine hydroxylase expressed in Escherichia coli. Comparison of resting and activated states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases. Isolation and characterization of the wild-type enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Structure/function relationships in human phenylalanine hydroxylase. Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

The cooperative binding of phenylalanine to phenylalanine 4-monooxygenase studied by 1H-NMR paramagnetic relaxation. Changes in water accessibility to the iron at the active site upon substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

The role of phenylalanine in structure-function relationships of phenylalanine hydroxylase revealed by radiation target analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Recombinant human phenylalanine hydroxylase is a substrate for the ubiquitin-conjugating enzyme system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

An amino-acid substitution involved in phenylketonuria is in linkage disequilibrium with DNA haplotype 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Founder effect of a prevalent phenylketonuria mutation in the Oriental population

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Raster3D Version 2.0. A program for photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Improved Fourier coefficients for maps using phases from partial structures with errors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Tight linkage between a splicing mutation and a specific DNA haplotype in phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Characterization of chimeric pterin-dependent hydroxylases: contributions of the regulatory domains of tyrosine and phenylalanine hydroxylase to substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Proline-dependent oligomerization with arm exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Domain structure and stability of human phenylalanine hydroxylase inferred from infrared spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

PKU mutations R408Q and F299C in Norway: haplotype associations, geographic distributions and phenotype characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Phenylketonuria missense mutations in the Mediterranean

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

Phenylalanine hydroxylase deficiency caused by a single base substitution in an exon of the human phenylalanine hydroxylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962

A prevalent missense mutation in Northern Europe associated with hyperphenylalaninaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.27.16962