(Q27851396)

13 November 2016

title

Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer (English)

1 reference

Journal of Clinical Investigation

PubMed publication ID

13 November 2016

0 references

1 reference

Jeffrey A Engelman

1

0 references

Toru Mukohara

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publication date

October 2006

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language of work or name

English

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published in

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volume

116

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issue

10

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page(s)

2695-706

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describes a project that uses

NCI-H3255GR

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ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1570180/fullTextXML

inferred from PubMed Central ID database lookup

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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27 November 2018

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Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

27 November 2018

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Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer

27 November 2018

1 reference

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27 November 2018

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Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation

27 November 2018

1 reference

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EGFR mutation and response of lung cancer to gefitinib

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1570180

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27 November 2018

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Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1570180

Cellular targets of gefitinib

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1570180

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants

27 November 2018

1 reference

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BCR-ABL point mutants isolated from patients with imatinib mesylate-resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 90.

27 November 2018

1 reference

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Pharmacodynamic studies of the epidermal growth factor receptor inhibitor ZD1839 in skin from cancer patients: histopathologic and molecular consequences of receptor inhibition

27 November 2018

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Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer Is correlated with survival.

27 November 2018

1 reference

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Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration

27 November 2018

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12 December 2020

Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase

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12 December 2020

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

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12 December 2020

Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression

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12 December 2020

Identifiers

DOI

10.1172/JCI28656

1 reference

1 reference

1 reference

PubMed publication ID

16906227

1 reference