(Q38361603)

2 September 2017

Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy (English)

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Kreil S

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Corbin AS

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La Rosée P

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Müller MC

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Lahaye T

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Hanfstein B

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Schoch C

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Cross NC

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Berger U

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Gschaidmeier H

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Hehlmann R

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1 November 2002

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2190-2196

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2402741

2 September 2017

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cites work

Chronic myeloid leukemia

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7 January 2021

Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study

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7 January 2021

Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study.

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7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Restoration of sensitivity to STI571 in STI571-resistant chronic myeloid leukemia cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Roots of clinical resistance to STI-571 cancer therapy

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Ph(+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: a study on 350 cases.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Minimal Residual Disease after Bone Marrow Transplant for Chronic Myeloid Leukaemia Detected by the Polymerase Chain Reaction

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Structural requirements for function of the Crkl adapter protein in fibroblasts and hematopoietic cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Analysis of the structural basis of specificity of inhibition of the Abl kinase by STI571.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

The P-loop--a common motif in ATP- and GTP-binding proteins

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Phosphorylation and structure-based functional studies reveal a positive and a negative role for the activation loop of the c-Abl tyrosine kinase.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Origin of multidrug resistance in cells with and without multidrug resistance genes: chromosome reassortments catalyzed by aneuploidy

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Cytogenetics of chronic myeloid leukaemia.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: a translational perspective.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402741

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402741

1 reference

Dimensions Publication ID

2 September 2017

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