(Q33944454)

30 July 2017

Origin of multidrug resistance in cells with and without multidrug resistance genes: chromosome reassortments catalyzed by aneuploidy (English)

1 reference

30 July 2017

multiple drug resistance

1 reference

1

P Duesberg

1 reference

30 July 2017

R Stindl

2

1 reference

PubMed ID

11553793

30 July 2017

R Hehlmann

series ordinal

3

1 reference

PubMed ID

11553793

30 July 2017

language of work or name

English

0 references

publication date

11 September 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

1 reference

30 July 2017

98

1 reference

30 July 2017

11283-11288

1 reference

30 July 2017

20

1 reference

A Study of the Relationship between Karyotype and Phenotype in Clones Lines of Strain Hela

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

ISOLATION AND STUDY OF MUTANTS FROM MAMMALIAN CELLS IN CULTURE

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

ANEUPLOIDY IN THE DEGENERATIVE PHASE OF SERIAL CULTIVATION OF HUMAN CELL STRAINS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

The chromosomes in ontogeny and oncogeny.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Role of chromosomes in cancerogenesis, as studied in serial tissue culture of mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Explaining the high mutation rates of cancer cells to drug and multidrug resistance by chromosome reassortments that are catalyzed by aneuploidy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Aneuploidy, the somatic mutation that makes cancer a species of its own.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

A family of drug transporters: the multidrug resistance-associated proteins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Aneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation but is found to support aneuploidy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Structural, mechanistic and clinical aspects of MRP1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Genomic imbalances associated with acquired resistance to platinum analogues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

How aneuploidy affects metabolic control and causes cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Expression of multidrug resistance protein-related genes in lung cancer: correlation with drug response.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Genetic instability of cancer cells is proportional to their degree of aneuploidy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Aneuploidy correlated 100% with chemical transformation of Chinese hamster cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

The cellular basis of tumor progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Multidrug resistance in breast cancer: a meta-analysis of MDR1/gp170 expression and its possible functional significance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Genetic instability in colorectal cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Cisplatin-DNA damage recognition proteins in human tumour extracts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Mechanisms of drug resistance in ovarian cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Molecular cytogenetics of multiple drug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

The toxicity of azidothymidine (AZT) on human and animal cells in culture at concentrations used for antiviral therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Metastatic variants are generated spontaneously at a high rate in mouse KHT tumor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Karyotype evolution and tumor development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Mammalian cell genetics. I. Selection and characterization of mutations auxotrophic for L-glutamine or resistant to 8-azaguanine in Chinese hamster cells in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Mutation rates in cells at different ploidy levels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Mutagenesis to aminopterin resistance in cultured hamster cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Chromosomal Variation and the Origin of Drug-Resistant Mutants in Mammalian Cell Lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Mutants of cultured chinese hamster cells deficient in adenine phosphoribosyl transferase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Reversion of the 8-azaguanine resistant phenotype of variant Chinese hamster cells treated with alkylating agents and 5-brono-2'-deoxyuridine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

On the nature of hereditable variation in cultured somatic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Aneuploidy and ageing: chromosome studies on a random sample of the population using G-banding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Origin of the resistance of leukaemic cells to folic acid antagonists.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201398998

P glycoprotein (P-gp) and drug resistance--time for reappraisal?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201398998

Drug resistance-associated marker Lrp for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201398998

New-age drug meets resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201398998

Acquired drug resistance is accompanied by modification in the karyotype and nuclear matrix of a rat carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201398998

When theories collide: experts develop different models for carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.201398998

STUDIES ON THYMIDINE KINASE IN CULTURED MOUSE FIBROBLASTS.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Chromosomal constitution and amethopterin resistance in cultured mouse cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Drug resistance: still on the learning curve.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Expression of P-glycoprotein and in vitro or in vivo resistance to doxorubicin and cisplatin in breast and ovarian cancers.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=58721

CYTOGENETICS OF MOUSE LEUKEMIA L1210. I. ASSOCIATION OF A SPECIFIC CHROMOSOME WITH DIHYDROFOLATE REDUCTASE ACTIVITY IN AMETHOPTERIN-TREATED SUBLINES

29 October 2018

1 reference

12 December 2020

Cytogenetically marked clones in human fibroblasts cultured from normal subjects

1 reference

12 December 2020

Effect of Ploidy and Mutagens on Bromodeoxyuridine Resistance in Haploid and Diploid Frog Cells

1 reference

12 December 2020

Correlation of chromosomal and physiologic changes in tumors

1 reference

12 December 2020

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

1 reference

12 December 2020

BIOCHEMICALLY MARKED VARIANTS OF THE SYRIAN HAMSTER FIBROBLAST CELL LINE BHK21 AND ITS DERIVATIVES

1 reference

12 December 2020

The effects of chemotherapy on the kinetics of leukemic cell behavior

1 reference

12 December 2020

Are centrosomes or aneuploidy the key to cancer?

1 reference

12 December 2020

Polyploidy--more is more or less

1 reference

12 December 2020

Diagnostic and prognostic value of DNA cytometry in gynecologic cytology

1 reference

12 December 2020

Nonrandom de novo chromosome aberrations in human lymphocytes and amniotic cells

1 reference

12 December 2020

Isolation and characterization of thymidine transport mutants of Chinese hamster cells

1 reference

12 December 2020

Value of P-glycoprotein, glutathione S-transferase pi, c-erbB-2, and p53 as prognostic factors in ovarian carcinomas

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.201398998

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference

PubMed ID

11553793