(Q27852177)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

main subject

phase II clinical trial

0 references

0 references

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Aimee M Crago

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Samuel Singer

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

4

Sandra P D'Angelo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

5

Mrinal M Gounder

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

Mark A Dickson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

William D Tap

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Mary Louise Keohan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Cristina R Antonescu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Li-Xuan Qin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Dustin D Rathbone

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Mercedes M Condy

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Yelena Ustoyev

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Gary K Schwartz

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

language of work or name

English

0 references

publication date

8 April 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Oncology

28 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

2024-2028

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

28 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Testing new regimens in patients with advanced soft tissue sarcoma: analysis of publications from the last 10 years.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

The CDKN2A/CDKN2B/CDK4/CCND1 pathway is pivotal in well-differentiated and dedifferentiated liposarcoma oncogenesis: an analysis of 104 tumors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Evaluation of well-differentiated/de-differentiated liposarcomas by high-resolution oligonucleotide array-based comparative genomic hybridization.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661937

Progression-free rate as the principal end-point for phase II trials in soft-tissue sarcomas

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23569312

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23569312

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1200/JCO.2012.46.5476

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23569312%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

2 references