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Dissecting the ER-associated degradation of a misfolded polytopic membrane protein
scientific article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
18191224
retrieved
1 December 2016
title
Dissecting the ER-associated degradation of a misfolded polytopic membrane protein
(English)
1 reference
stated in
PubMed
PubMed ID
18191224
retrieved
1 December 2016
main subject
E2 ubiquitin-conjugating protein UBC6 YER100W
1 reference
stated in
GOA release 2020-03-11
ATP-binding cassette a-factor transporter STE6 YKL209C
1 reference
stated in
GOA release 2020-03-11
E3 ubiquitin-protein ligase SSM4 YIL030C
1 reference
stated in
GOA release 2020-03-11
membrane protein
1 reference
based on heuristic
inferred from title
author name string
Susan Michaelis
series ordinal
3
0 references
Kunio Nakatsukasa
series ordinal
1
0 references
Jeffrey L Brodsky
series ordinal
4
0 references
Gregory Huyer
series ordinal
2
0 references
language of work or name
English
0 references
publication date
11 January 2008
0 references
published in
Cell
1 reference
stated in
PubMed
PubMed ID
18191224
retrieved
1 December 2016
volume
132
0 references
page(s)
101-12
0 references
issue
1
0 references
cites work
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Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein
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Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control
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Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains
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A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation
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In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation
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Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation
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Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.
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The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
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20 March 2017
Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms
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20 March 2017
Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
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PubMed Central
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20 March 2017
Functional interaction of cytosolic hsp70 and a DnaJ-related protein, Ydj1p, in protein translocation in vivo
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PubMed Central
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20 March 2017
ERAD: the long road to destruction
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20 March 2017
Roles of molecular chaperones in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD)
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The 26S proteasome: a molecular machine designed for controlled proteolysis
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Membrane chaperone Shr3 assists in folding amino acid permeases preventing precocious ERAD.
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29 September 2017
Small heat-shock proteins select deltaF508-CFTR for endoplasmic reticulum-associated degradation
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PubMed Central
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29 September 2017
p97 functions as an auxiliary factor to facilitate TM domain extraction during CFTR ER-associated degradation
1 reference
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PubMed Central
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29 September 2017
Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219389
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29 September 2017
Endoplasmic reticulum-associated degradation
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PubMed Central
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29 September 2017
Delivery of ubiquitinated substrates to protein-unfolding machines
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PubMed Central
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29 September 2017
The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags
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29 September 2017
Cystic fibrosis transmembrane conductance regulator degradation depends on the lectins Htm1p/EDEM and the Cdc48 protein complex in yeast
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PubMed Central
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29 September 2017
Dependence of endoplasmic reticulum-associated degradation on the peptide binding domain and concentration of BiP.
1 reference
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PubMed Central
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29 September 2017
For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection
1 reference
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PubMed Central
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29 September 2017
Endoproteolytic activity of the proteasome
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PubMed Central
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29 September 2017
Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast
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PubMed Central
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29 September 2017
Dynamic association of proteasomal machinery with the centrosome
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PubMed Central
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29 September 2017
Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.
1 reference
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PubMed Central
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29 September 2017
Ste6p mutants defective in exit from the endoplasmic reticulum (ER) reveal aspects of an ER quality control pathway in Saccharomyces cerevisiae
1 reference
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PubMed Central
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29 September 2017
Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP.
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29 September 2017
Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.
1 reference
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PubMed Central
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29 September 2017
Cytoplasmic Hsp70 promotes ubiquitination for endoplasmic reticulum-associated degradation of a misfolded mutant of the yeast plasma membrane ATPase, PMA1.
1 reference
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PubMed Central
reference URL
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2 June 2018
A 'distributed degron' allows regulated entry into the ER degradation pathway
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219389
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2 June 2018
Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219389
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2 June 2018
Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219389
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27 November 2018
A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219389
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27 November 2018
Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219389
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27 November 2018
Reconstitution of membrane proteolysis by FtsH.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2219389
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27 November 2018
Evidence that endoplasmic reticulum (ER)-associated degradation of cystic fibrosis transmembrane conductance regulator is linked to retrograde translocation from the ER membrane
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18191224
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Proteasome-mediated protein processing by bidirectional degradation initiated from an internal site
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18191224
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18191224
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18191224
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18191224
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Folding and quality control of the VHL tumor suppressor proceed through distinct chaperone pathways
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18191224
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELL.2007.11.023
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Fatcat
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https://api.fatcat.wiki/v0/release/zdh3a4alqbgj3frr52zdzvkmii
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30 July 2022
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Fatcat ID
release_zdh3a4alqbgj3frr52zdzvkmii
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OpenCitations bibliographic resource ID
2061423
1 reference
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Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2061423
PMCID
2219389
1 reference
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Fatcat
reference URL
https://api.fatcat.wiki/v0/release/zdh3a4alqbgj3frr52zdzvkmii
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30 July 2022
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PubMed ID
18191224
1 reference
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Fatcat
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https://api.fatcat.wiki/v0/release/zdh3a4alqbgj3frr52zdzvkmii
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ResearchGate publication ID
5660741
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