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Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8.
scientific article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
12399377
retrieved
1 December 2016
title
Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8.
(English)
1 reference
stated in
PubMed
PubMed ID
12399377
retrieved
1 December 2016
main subject
Saccharomyces cerevisiae
0 references
Esc8p YOL017W
1 reference
stated in
GOA release 2020-03-11
Phosphatidylinositol-binding protein SCS2 YER120W
1 reference
stated in
GOA release 2020-03-11
author name string
Guido Cuperus
series ordinal
1
0 references
David Shore
series ordinal
2
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language of work or name
English
0 references
publication date
October 2002
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published in
Genetics
1 reference
stated in
PubMed
PubMed ID
12399377
retrieved
1 December 2016
volume
162
0 references
page(s)
633-45
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issue
2
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cites work
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The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects
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A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast
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A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR.
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The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p
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Mediator of Transcriptional Regulation
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A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.
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The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
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Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme.
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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
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Two paralogs involved in transcriptional silencing that antagonistically control yeast life span
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Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity
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Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
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20 March 2017
The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism
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Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.
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20 March 2017
Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.
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20 March 2017
Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing
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20 March 2017
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.
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20 March 2017
Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.
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20 March 2017
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability
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PubMed Central
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20 March 2017
The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription
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20 March 2017
A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.
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20 March 2017
Basic local alignment search tool
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20 March 2017
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
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20 March 2017
Elevated recombination rates in transcriptionally active DNA
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20 March 2017
A new efficient gene disruption cassette for repeated use in budding yeast
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20 March 2017
Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription
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20 March 2017
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
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PubMed Central
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20 March 2017
Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast
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7 April 2017
Transcriptional silencing in yeast is associated with reduced nucleosome acetylation
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PubMed Central
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7 April 2017
The RNA polymerase II holoenzyme and its implications for gene regulation
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7 April 2017
The molecular biology of the SIR proteins
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PubMed Central
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29 September 2017
Sir2p exists in two nucleosome-binding complexes with distinct deacetylase activities
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PubMed Central
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29 September 2017
Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells
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29 September 2017
Locus specificity determinants in the multifunctional yeast silencing protein Sir2
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PubMed Central
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29 September 2017
High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating-type locus HMRa
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29 September 2017
Characterization of the imitation switch subfamily of ATP-dependent chromatin-remodeling factors in Saccharomyces cerevisiae
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PubMed Central
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29 September 2017
The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities
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29 September 2017
HST1, a new member of the SIR2 family of genes
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29 September 2017
Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure.
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PubMed Central
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29 September 2017
SPT13 (GAL11) of Saccharomyces cerevisiae negatively regulates activity of the MCM1 transcription factor in Ty1 elements
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PubMed Central
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29 September 2017
Perioperative mortality of elective abdominal aortic aneurysm surgery. A clinical prediction rule based on literature and individual patient data
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29 September 2017
Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.
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PubMed Central
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29 September 2017
Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length
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PubMed Central
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29 September 2017
The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo
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PubMed Central
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2 June 2018
The yeast HRS1 gene is involved in positive and negative regulation of transcription and shows genetic characteristics similar to SIN4 and GAL11.
1 reference
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PubMed Central
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2 June 2018
Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.
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PubMed Central
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2 June 2018
Epigenetic switching of transcriptional states: cis- and trans-acting factors affecting establishment of silencing at the HMR locus in Saccharomyces cerevisiae
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PubMed Central
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2 June 2018
The yeast GAL11 protein is involved in regulation of the structure and the position effect of telomeres
1 reference
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PubMed Central
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2 June 2018
DNA replication-independent silencing in S. cerevisiae.
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PubMed Central
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27 November 2018
Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins.
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PubMed Central
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27 November 2018
Pch2 links chromatin silencing to meiotic checkpoint control.
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PubMed Central
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27 November 2018
Chromatin-remodeling factors: machines that regulate?
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27 November 2018
Telomere maintenance is dependent on activities required for end repair of double-strand breaks.
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PubMed Central
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27 November 2018
Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres.
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PubMed Central
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27 November 2018
Yeast heterochromatin: regulation of its assembly and inheritance by histones
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27 November 2018
Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12399377
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12399377
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Establishment of transcriptional silencing in the absence of DNA replication
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12399377
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Silenced chromatin is permissive to activator binding and PIC recruitment
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12399377
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
GAL11P: a yeast mutation that potentiates the effect of weak GAL4-derived activators
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12399377
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
PMCID
1462306
0 references
PubMed ID
12399377
1 reference
stated in
PubMed
PubMed ID
12399377
retrieved
1 December 2016
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