(Q27933026)

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Half of Saccharomyces cerevisiae carbamoyl phosphate synthetase produces and channels carbamoyl phosphate to the fused aspartate transcarbamoylase domain

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scholarly article

1 reference

1 December 2016

Half of Saccharomyces cerevisiae carbamoyl phosphate synthetase produces and channels carbamoyl phosphate to the fused aspartate transcarbamoylase domain (English)

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1 December 2016

Saccharomyces cerevisiae

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Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase YJL130C

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GOA release 2020-03-11

author name string

V Serre

1

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H Guy

2

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B Penverne

3

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M Lux

4

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A Rotgeri

5

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D Evans

6

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G Hervé

7

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language of work or name

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publication date

20 August 1999

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Journal of Biological Chemistry

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1 December 2016

274

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23794-801

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34

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Carbamoylphosphate synthetase from Pseudomonas aeruginosa. Subunit composition, kinetic analysis and regulation

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Reversible dissociation of carbamyl phosphate synthetase into a regulated synthesis subunit and a subunit required for glutamine utilization

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Aggregation states and catalytic properties of the multienzyme complex catalyzing the initial steps of pyrimidine biosynthesis in rat liver

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Controlled proteolysis of the multifunctional protein that initiates pyrimidine biosynthesis in mammalian cells: evidence for discrete structural domains

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21 January 2018

Evidence for an Activated Form of Carbon Dioxide in the Reaction Catalyzed by Escherichia coli Carbamyl Phosphate Synthetase*

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Novel mechanism for carbamoyl-phosphate synthetase: a nucleotide switch for functionally equivalent domains

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Organization of the yeast URA2 gene: identification of a defective dihydroorotase-like domain in the multifunctional carbamoylphosphate synthetase-aspartate transcarbamylase complex.

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The rudimentary gene of Drosophila melanogaster encodes four enzymic functions.

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The carB gene of Escherichia coli: a duplicated gene coding for the large subunit of carbamoyl-phosphate synthetase

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21 January 2018

The aspartate transcarbamylase and carbamoyl phosphate synthetase of yeast: A multi-functional enzyme complex

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The carbamoyl phosphate synthetase-aspartate transcarbamoylase complex of Saccharomyces cerevisiae: molecular and cellular aspects

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Characterization of the aspartate carbamoyltransferase subunit obtained from a multienzyme aggregate in the pyrimidine pathway of yeast. Activity and physical properties

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Regulation of activity of carbamoyl phosphate synthetase from mouse spleen

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Allosteric regulation and substrate channeling in multifunctional pyrimidine biosynthetic complexes: analysis of isolated domains and yeast-mammalian chimeric proteins.

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Escherichia coli carbamoyl-phosphate synthetase: domains of glutaminase and synthetase subunit interaction

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Pressure-induced dissociation of carbamoyl-phosphate synthetase domains. The catalytically active form is dimeric

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A generalized theory of the transition time for sequential enzyme reactions

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Carbamoyl phosphate biosynthesis and partition in pyrimidine and arginine pathways of Escherichia coli. In situ properties of carbamoyl-phosphate synthase, ornithine transcarbamylase and aspartate transcarbamylase in permeabilized cells

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Control of pyrimidine biosynthesis in mammalian tissues. V. Regulation of glutamine-dependent carbamyl phosphate synthetase: activation by 5-phosphoribosyl 1-pyrophosphate and inhibition by uridine triphosphate.

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Sequence analysis and expression of the arginine-deiminase and carbamate-kinase genes of Pseudomonas aeruginosa

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Crystalline carbamate kinase

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Carbamate kinase from Enterococcus faecalis and Enterococcus faecium--cloning of the genes, studies on the enzyme expressed in Escherichia coli, and sequence similarity with N-acetyl-L-glutamate kinase.

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Nucleotide sequence of the pyrimidine specific carbamoyl phosphate synthetase, a part of the yeast multifunctional protein encoded by the URA2 gene.

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The evolutionary history of the first three enzymes in pyrimidine biosynthesis

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Structure-function studies in carbamoyl phosphate synthetases

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Structural modeling and electrostatic properties of aspartate transcarbamylase from Saccharomyces cerevisiae.

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Identification of the ATP binding sites of the carbamyl phosphate synthetase domain of the Syrian hamster multifunctional protein CAD by affinity labeling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine

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Role of conserved residues within the carboxy phosphate domain of carbamoyl phosphate synthetase

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Comparison of the functional differences for the homologous residues within the carboxy phosphate and carbamate domains of carbamoyl phosphate synthetase.

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Structure of carbamoyl phosphate synthetase: a journey of 96 A from substrate to product

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The carbamate kinase-like carbamoyl phosphate synthetase of the hyperthermophilic archaeon Pyrococcus furiosus, a missing link in the evolution of carbamoyl phosphate biosynthesis

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Regulation of the mammalian carbamoyl-phosphate synthetase II by effectors and phosphorylation. Altered affinity for ATP and magnesium ions measured using the ammonia-dependent part reaction

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Regulation and mutation affecting a glutamine dependent formation of carbamyl phosphate in Escherichia coli

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Uridylic acid synthesis in Ehrlich ascites carcinoma. Properties, subcellular distribution, and nature of enzyme complexes of the six biosynthetic enzymes

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Molecular characterization of a Dictyostelium discoideum gene encoding a multifunctional enzyme of the pyrimidine pathway

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Function of the major synthetase subdomains of carbamyl-phosphate synthetase

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A study of the aspartate transcarbamylase activity of yeast

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Activation by 5-phosphoribosyl 1-pyrophosphate of glutamine-dependent carbamyl phosphate synthetase from mouse spleen

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21 January 2018

In situ behavior of the pyrimidine pathway enzymes in Saccharomyces cerevisiae. 3. Catalytic and regulatory properties of carbamylphosphate synthetase: channeling of carbamylphosphate to aspartate transcarbamylase

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In situ behavior of the pyrimidine pathway enzymes in Saccharomyces cerevisiae. 4. The channeling of carbamylphosphate to aspartate transcarbamylase and its partition in the pyrimidine and arginine pathways

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A reciprocal allosteric mechanism for efficient transfer of labile intermediates between active sites in CAD, the mammalian pyrimidine-biosynthetic multienzyme polypeptide

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Allosteric regulation of carbamoylphosphate synthetase-aspartate transcarbamylase multifunctional protein of Saccharomyces cerevisiae: selection, mapping and identification of missense mutations define three regions involved in feedback inhibition b

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The biosynthesis of carbamoyl phosphate in Saccharomyces cerevisiae

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21 January 2018

Control of Escherichia coli Carbamyl Phosphate Synthetase by Purine and Pyrimidine Nucleotides*

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Homology and mutagenesis studies of hamster dihydroorotase

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Purification and characterization of carbamoyl-phosphate synthetase from the deep-sea hyperthermophilic archaebacterium Pyrococcus abyssi

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21 January 2018

Affinity cleavage of carbamoyl-phosphate synthetase I localizes regions of the enzyme interacting with the molecule of ATP that phosphorylates carbamate

1 reference

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21 January 2018

Allosteric effects of carbamoyl phosphate synthetase from Escherichia coli are entropy-driven

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21 January 2018

Identifiers

10.1074/JBC.274.34.23794

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1 reference

1 December 2016

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