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Pseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation
scientific article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
18519589
retrieved
1 December 2016
title
Pseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation
(English)
1 reference
stated in
PubMed
PubMed ID
18519589
retrieved
1 December 2016
main subject
cell biology
0 references
proteolysis
1 reference
based on heuristic
inferred from title
Acm1p YPL267W
1 reference
stated in
GOA release 2020-03-11
phosphorylation
1 reference
based on heuristic
inferred from title
author name string
Denis Ostapenko
series ordinal
1
0 references
Janet L Burton
series ordinal
2
0 references
Ruiwen Wang
series ordinal
3
0 references
Mark J Solomon
series ordinal
4
0 references
language of work or name
English
0 references
publication date
August 2008
0 references
published in
Molecular and Cellular Biology
1 reference
stated in
PubMed
PubMed ID
18519589
retrieved
1 December 2016
volume
28
0 references
page(s)
4653-64
0 references
issue
15
0 references
cites work
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Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase
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Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor
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Cdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteins
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Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1
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Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase
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E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)
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Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex
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Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
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Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex
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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
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14-3-3 proteins are essential for RAS/MAPK cascade signaling during pseudohyphal development in S. cerevisiae
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Cyclin is degraded by the ubiquitin pathway
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20 March 2017
Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms
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20 March 2017
Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex
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20 March 2017
Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint
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20 March 2017
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20 March 2017
Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins
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20 March 2017
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1
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20 March 2017
The anaphase-promoting complex: proteolysis in mitosis and beyond
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20 March 2017
Mitotic regulation of the APC activator proteins CDC20 and CDH1
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20 March 2017
The anaphase promoting complex/cyclosome: a machine designed to destroy
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7 April 2017
A chemical switch for inhibitor-sensitive alleles of any protein kinase
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7 April 2017
The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae
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7 April 2017
Yeast Hct1 is a regulator of Clb2 cyclin proteolysis
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7 April 2017
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p
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7 April 2017
Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway
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7 April 2017
Guide to yeast genetics and molecular biology
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7 April 2017
Cdc28 and Cdc14 control stability of the anaphase-promoting complex inhibitor Acm1.
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29 September 2017
Cdc20: a WD40 activator for a cell cycle degradation machine
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29 September 2017
Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases
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29 September 2017
Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C
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29 September 2017
Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint
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29 September 2017
The APC/C inhibitor, Emi1, is essential for prevention of rereplication
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29 September 2017
Precise destruction: an emerging picture of the APC.
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29 September 2017
Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae
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PubMed Central
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29 September 2017
Assembly of an APC-Cdh1-substrate complex is stimulated by engagement of a destruction box.
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29 September 2017
Phosphorylation by Cak1 regulates the C-terminal domain kinase Ctk1 in Saccharomyces cerevisiae
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29 September 2017
APC/C and SCF: controlling each other and the cell cycle
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29 September 2017
The anaphase-promoting complex: it's not just for mitosis any more.
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29 September 2017
Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1.
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PubMed Central
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29 September 2017
D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p
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29 September 2017
Hsl1p, a Swe1p inhibitor, is degraded via the anaphase-promoting complex
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PubMed Central
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29 September 2017
Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint
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29 September 2017
Cut2 proteolysis required for sister-chromatid seperation in fission yeast
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29 September 2017
14-3-3 proteins: potential roles in vesicular transport and Ras signaling in Saccharomyces cerevisiae
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29 September 2017
The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosis.
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2 June 2018
Separation of sister chromatids in mitosis requires the Drosophila pimples product, a protein degraded after the metaphase/anaphase transition.
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2 June 2018
Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue.
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27 November 2018
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway
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27 November 2018
The APC subunit Doc1 promotes recognition of the substrate destruction box.
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27 November 2018
Cdc28/Cdk1 regulates spindle pole body duplication through phosphorylation of Spc42 and Mps1.
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27 November 2018
Purification and Assay of the Budding Yeast Anaphase‐Promoting Complex
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18519589
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Anaphase inactivation of the spindle checkpoint
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18519589
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Two different modes of cyclin clb2 proteolysis during mitosis in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18519589
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.00055-08
1 reference
stated in
PubMed
PubMed ID
18519589
retrieved
1 December 2016
PMCID
2493364
0 references
PubMed ID
18519589
1 reference
stated in
PubMed
PubMed ID
18519589
retrieved
1 December 2016
ResearchGate publication ID
51396183
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