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MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p
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scholarly article
1 reference
stated in
PubMed
PubMed ID
10704439
retrieved
1 December 2016
title
MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p
(English)
1 reference
stated in
PubMed
PubMed ID
10704439
retrieved
1 December 2016
main subject
mitotic checkpoint complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0033597
Ubiquitin-protein transferase activating protein CDC20 YGL116W
1 reference
stated in
GOA release 2020-03-11
Bub3p YOR026W
1 reference
stated in
GOA release 2020-03-11
Mad3p YJL013C
1 reference
stated in
GOA release 2020-03-11
Protein kinase BUB1 YGR188C
1 reference
stated in
GOA release 2020-03-11
Coiled-coil domain-containing protein MAD1 YGL086W
1 reference
stated in
GOA release 2020-03-11
Spindle checkpoint protein MAD2 YJL030W
1 reference
stated in
GOA release 2020-03-11
author name string
K G Hardwick
series ordinal
1
0 references
R C Johnston
series ordinal
2
0 references
D L Smith
series ordinal
3
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A W Murray
series ordinal
4
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language of work or name
English
0 references
publication date
6 March 2000
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published in
Journal of Cell Biology
1 reference
stated in
PubMed
PubMed ID
10704439
retrieved
1 December 2016
volume
148
0 references
page(s)
871-82
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issue
5
0 references
cites work
APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5.
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC
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PubMed Central
reference URL
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20 March 2017
The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins
1 reference
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PubMed Central
reference URL
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20 March 2017
Lesions in many different spindle components activate the spindle checkpoint in the budding yeast Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
Bifurcation of the mitotic checkpoint pathway in budding yeast
1 reference
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PubMed Central
reference URL
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20 March 2017
Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1
1 reference
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PubMed Central
reference URL
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20 March 2017
The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
Mutations of mitotic checkpoint genes in human cancers
1 reference
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PubMed Central
reference URL
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20 March 2017
Budding yeast Cdc20: a target of the spindle checkpoint.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
The spindle checkpoint.
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
A novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in cyclin proteolysis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
Identification of a human mitotic checkpoint gene: hsMAD2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
retrieved
20 March 2017
The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
retrieved
20 March 2017
The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
Feedback control of mitosis in budding yeast
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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20 March 2017
Localization of Mad2 to kinetochores depends on microtubule attachment, not tension
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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7 April 2017
Yeast Hct1 is a regulator of Clb2 cyclin proteolysis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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7 April 2017
Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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7 April 2017
How cells get the right chromosomes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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7 April 2017
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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7 April 2017
Mitotic forces control a cell-cycle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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7 April 2017
Guide to yeast genetics and molecular biology
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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7 April 2017
Pds1p of budding yeast has dual roles: inhibition of anaphase initiation and regulation of mitotic exit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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29 September 2017
Pds1 and Esp1 control both anaphase and mitotic exit in normal cells and after DNA damage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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29 September 2017
A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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29 September 2017
Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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29 September 2017
Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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29 September 2017
Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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29 September 2017
The spindle assembly checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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29 September 2017
Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
retrieved
29 September 2017
Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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29 September 2017
Single-step purification of shuttle vectors from yeast for high frequency back-transformation into E. coli
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
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29 September 2017
Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
retrieved
2 June 2018
GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174553
retrieved
2 June 2018
The spindle-assembly checkpoint: aiming for a perfect mitosis, every time.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1083%2FJCB.148.5.871
retrieved
21 January 2018
Identifiers
DOI
10.1083/JCB.148.5.871
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1524611
OpenCitations bibliographic resource ID
1524611
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1524611
PMCID
2174553
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1524611
PubMed ID
10704439
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1524611
ResearchGate publication ID
12612153
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