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A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication
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scholarly article
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stated in
PubMed
PubMed ID
23236290
retrieved
1 December 2016
title
A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication
(English)
1 reference
stated in
PubMed
PubMed ID
23236290
retrieved
1 December 2016
main subject
Serine/threonine/tyrosine protein kinase MCK1 YNL307C
1 reference
stated in
GOA release 2020-03-11
author name string
Amy E Ikui
series ordinal
1
0 references
Valentina Rossio
series ordinal
2
0 references
Lea Schroeder
series ordinal
3
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Satoshi Yoshida
series ordinal
4
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language of work or name
English
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publication date
2012
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published in
PLOS Genetics
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stated in
PubMed
PubMed ID
23236290
retrieved
1 December 2016
volume
8
0 references
page(s)
e1003099
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issue
12
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copyright license
Creative Commons Attribution 4.0 International
start time
6 December 2012
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
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cites work
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1 reference
stated in
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516531
retrieved
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1 reference
stated in
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516531
retrieved
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1 reference
stated in
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516531
retrieved
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retrieved
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retrieved
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retrieved
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1 reference
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1 reference
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retrieved
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stated in
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retrieved
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1 reference
stated in
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reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516531
retrieved
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1 reference
stated in
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516531
retrieved
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1 reference
stated in
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reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516531
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3516531
retrieved
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Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.
1 reference
stated in
PubMed Central
reference URL
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retrieved
2 June 2018
The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003099
retrieved
21 January 2018
Regulation of the localization and stability of Cdc6 in living yeast cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003099
retrieved
21 January 2018
Glycogen Synthase Kinase-3 from Rabbit Skeletal Muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003099
retrieved
21 January 2018
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003099
retrieved
21 January 2018
Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23236290
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Cdc6 protein is ubiquitinated in vivo for proteolysis in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23236290
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1371/JOURNAL.PGEN.1003099
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PMCID
3516531
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PubMed ID
23236290
1 reference
stated in
PubMed
PubMed ID
23236290
retrieved
1 December 2016
ResearchGate publication ID
233909604
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