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Activation of 5'-3' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast
scientific article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
22570495
retrieved
1 December 2016
title
Activation of 5'-3' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast
(English)
1 reference
stated in
PubMed
PubMed ID
22570495
retrieved
1 December 2016
main subject
regulation of exoribonuclease activity
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1901917
positive regulation of exoribonuclease activity
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1901919
exoribonuclease activator activity
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0044692
negative regulation of exoribonuclease activity
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1901918
5'-(N(7)-methyl 5'-triphosphoguanosine)-(mRNA) diphosphatase YLR270W
1 reference
stated in
GOA release 2020-03-11
author
Megerditch Kiledjian
series ordinal
3
0 references
Ciarán Condon
series ordinal
4
0 references
Lionel Benard
1 reference
stated in
ORCID Public Data File 2021
author name string
Flore Sinturel
series ordinal
1
0 references
Dominique Bréchemier-Baey
series ordinal
2
0 references
Lionel Bénard
series ordinal
5
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language of work or name
English
0 references
publication date
22 May 2012
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published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
PubMed
PubMed ID
22570495
retrieved
1 December 2016
volume
109
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issue
21
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page(s)
8264-9
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ImageQuant
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3361377/fullTextXML
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inferred from PubMed Central ID database lookup
cites work
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PubMed Central
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Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae
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20 March 2017
Structure and function of the 5′→3′ exoribonuclease Rat1 and its activating partner Rai1
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Dcs2, a novel stress-induced modulator of m7GpppX pyrophosphatase activity that locates to P bodies.
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Scavenger decapping activity facilitates 5' to 3' mRNA decay
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The 'scavenger' m7GpppX pyrophosphatase activity of Dcs1 modulates nutrient-induced responses in yeast
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The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases
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PubMed Central
reference URL
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Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively
1 reference
stated in
PubMed Central
reference URL
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The highways and byways of mRNA decay
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Turnover mechanisms of the stable yeast PGK1 mRNA
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Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure
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Real-time fluorescence detection of exoribonucleases
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Trans-acting antisense RNAs mediate transcriptional gene cosuppression in S. cerevisiae
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29 September 2017
Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1.
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A cryptic unstable transcript mediates transcriptional trans-silencing of the Ty1 retrotransposon in S. cerevisiae
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Involvement of Dcr1 in post-transcriptional regulation of gene expression in Schizosaccharomyces pombe
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29 September 2017
Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function
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Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast
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Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis
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Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease
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A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae.
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29 September 2017
Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening
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29 September 2017
rar mutations which increase artificial chromosome stability in Saccharomyces cerevisiae identify transcription and recombination proteins
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29 September 2017
Fragments of the internal transcribed spacer 1 of pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5'----3' exoribonuclease 1
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29 September 2017
The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination
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2 June 2018
Molecular cloning and sequencing of cDNA for yeast porin, an outer mitochondrial membrane protein: a search for targeting signal in the primary structure
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PubMed Central
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2 June 2018
XUTs are a class of Xrn1-sensitive antisense regulatory non-coding RNA in yeast.
1 reference
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Crossref
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https://api.crossref.org/works/10.1073%2FPNAS.1120090109
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21 January 2018
Sodium-induced GCN4 expression controls the accumulation of the 5' to 3' RNA degradation inhibitor, 3'-phosphoadenosine 5'-phosphate
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.1120090109
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21 January 2018
Analysis of mRNA decapping
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22570495
retrieved
12 December 2020
based on heuristic
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Identifiers
DOI
10.1073/PNAS.1120090109
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ADS bibcode
2012PNAS..109.8264S
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PMCID
3361377
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PubMed ID
22570495
1 reference
stated in
PubMed
PubMed ID
22570495
retrieved
1 December 2016
ResearchGate publication ID
224926389
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