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Nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast
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scholarly article
1 reference
stated in
PubMed
PubMed ID
18573877
retrieved
1 December 2016
title
Nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast
(English)
1 reference
stated in
PubMed
PubMed ID
18573877
retrieved
1 December 2016
main subject
cell biology
0 references
Gamma-tubulin complex subunit SPC72 YAL047C
1 reference
stated in
GOA release 2020-03-11
Exportin CRM1 YGR218W
1 reference
stated in
GOA release 2020-03-11
author name string
Anja Neuber
series ordinal
1
0 references
Jacqueline Franke
series ordinal
2
0 references
Angelika Wittstruck
series ordinal
3
0 references
Gabriel Schlenstedt
series ordinal
4
0 references
Thomas Sommer
series ordinal
5
0 references
Katrin Stade
series ordinal
6
0 references
language of work or name
English
0 references
publication date
September 2008
0 references
published in
Molecular and Cellular Biology
1 reference
stated in
PubMed
PubMed ID
18573877
retrieved
1 December 2016
volume
28
0 references
page(s)
5348-58
0 references
issue
17
0 references
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2519715/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
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The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicing
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RanBP3 influences interactions between CRM1 and its nuclear protein export substrates
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Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export
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Yeast Ran-binding protein 1 (Yrb1) shuttles between the nucleus and cytoplasm and is exported from the nucleus via a CRM1 (XPO1)-dependent pathway
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Time-lapse video microscopy analysis reveals astral microtubule detachment in the yeast spindle pole mutant cnm67
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A nuclear export signal prevents Saccharomyces cerevisiae Hsp70 Ssb1p from stimulating nuclear localization signal-directed nuclear transport
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Spc29p is a component of the Spc110p subcomplex and is essential for spindle pole body duplication
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Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor
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Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1.
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Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
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A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export
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CRM1 is an export receptor for leucine-rich nuclear export signals
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519715
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Exportin 1 (Crm1p) is an essential nuclear export factor
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519715
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Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein
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PubMed Central
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The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88
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Overexpression of yeast homologs of the mammalian checkpoint gene RCC1 suppresses the class of alpha-tubulin mutations that arrest with excess microtubules
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Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
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20 March 2017
Mammalian RanBP1 regulates centrosome cohesion during mitosis
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7 April 2017
The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export
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Characterization of centrosomal association of nucleophosmin/B23 linked to Crm1 activity
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20 March 2017
CRM1 is responsible for intracellular transport mediated by the nuclear export signal
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7 April 2017
Identification of a signal for rapid export of proteins from the nucleus
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7 April 2017
Centrosome composition and microtubule anchoring mechanisms
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PubMed Central
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7 April 2017
Evidence for a role of CRM1 in signal-mediated nuclear protein export
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519715
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7 April 2017
Mitosis in living budding yeast: anaphase A but no metaphase plate
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7 April 2017
Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae
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7 April 2017
Behavior of spindles and spindle plaques in the cell cycle and conjugation of Saccharomyces cerevisiae
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7 April 2017
Mitotic spindle morphogenesis: Ran on the microtubule cytoskeleton and beyond
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29 September 2017
Dynamic nuclear pore complexes: life on the edge.
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29 September 2017
New CRIME plots. Ran and transport factors regulate mitosis
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29 September 2017
Crm1 is a mitotic effector of Ran-GTP in somatic cells
1 reference
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PubMed Central
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29 September 2017
Leucine-rich nuclear-export signals: born to be weak
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29 September 2017
Nuclear export of RNA.
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PubMed Central
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29 September 2017
The budding yeast spindle pole body: structure, duplication, and function
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29 September 2017
Karyopherins: from nuclear-transport mediators to nuclear-function regulators
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29 September 2017
The nuclear pore complex: nucleocytoplasmic transport and beyond
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29 September 2017
Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.
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29 September 2017
Nucleocytoplasmic transport: taking an inventory
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29 September 2017
The XMAP215 homologue Stu2 at yeast spindle pole bodies regulates microtubule dynamics and anchorage
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29 September 2017
Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles
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29 September 2017
The Ran GTPase cycle is required for yeast nuclear pore complex assembly
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29 September 2017
The Ran GTPase: theme and variations
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29 September 2017
Synchronization procedures
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PubMed Central
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29 September 2017
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29 September 2017
The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast Ran binding protein 1 (Yrb1p).
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29 September 2017
Running on Ran: nuclear transport and the mitotic spindle.
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29 September 2017
Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities
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29 September 2017
Role of importin-beta in coupling Ran to downstream targets in microtubule assembly
1 reference
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29 September 2017
Importin beta is a mitotic target of the small GTPase Ran in spindle assembly
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PubMed Central
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29 September 2017
The spindle cycle in budding yeast
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29 September 2017
Nud1p links astral microtubule organization and the control of exit from mitosis
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29 September 2017
The fission yeast ran GTPase is required for microtubule integrity
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29 September 2017
Identification of novel Saccharomyces cerevisiae proteins with nuclear export activity: cell cycle-regulated transcription factor ace2p shows cell cycle-independent nucleocytoplasmic shuttling
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29 September 2017
Spindle pole body duplication: a model for centrosome duplication?
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29 September 2017
gamma-tubulin complexes: binding to the centrosome, regulation and microtubule nucleation
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29 September 2017
Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle.
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PubMed Central
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29 September 2017
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking
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PubMed Central
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29 September 2017
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519715
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29 September 2017
Spc98p directs the yeast gamma-tubulin complex into the nucleus and is subject to cell cycle-dependent phosphorylation on the nuclear side of the spindle pole body
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PubMed Central
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29 September 2017
A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519715
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29 September 2017
The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519715
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29 September 2017
Catalysis of guanine nucleotide exchange of Ran by RCC1 and stimulation of hydrolysis of Ran-bound GTP by Ran-GAP1.
1 reference
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PubMed Central
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2 June 2018
A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519715
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27 November 2018
Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519715
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27 November 2018
SPC72: a spindle pole component required for spindle orientation in the yeast Saccharomyces cerevisiae
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18573877
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A RanBP1 mutation which does not visibly affect nuclear import may reveal additional functions of the ran GTPase system
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18573877
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18573877
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.02043-07
1 reference
stated in
PubMed
PubMed ID
18573877
retrieved
1 December 2016
Fatcat ID
release_vckv735ywjb6dg6kvzlh66eqt4
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/vckv735ywjb6dg6kvzlh66eqt4
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
2519715
0 references
PubMed ID
18573877
1 reference
stated in
PubMed
PubMed ID
18573877
retrieved
1 December 2016
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