(Q27976475)

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Malaria parasite signal peptide peptidase is an ER-resident protease required for growth but not for invasion

scientific article (publication date: November 2012)

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title

Malaria parasite signal peptide peptidase is an ER-resident protease required for growth but not for invasion (English)

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main subject

malaria

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signal peptide peptidase

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stated in

GeneDB

retrieved

12 September 2018

signal peptide peptidase, putative

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stated in

GeneDB

retrieved

19 December 2018

microbial invasion into a host organism

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Elizabeth S Zuccala

3

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Danny W Wilson

object named as

Danny W Wilson

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2

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Jake Baum

object named as

Jake Baum

series ordinal

7

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James Beeson

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5

object named as

James G Beeson

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Stuart A Ralph

object named as

Stuart A Ralph

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6

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author name string

Danushka S Marapana

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1

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Chaitali D Dekiwadia

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4

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language of work or name

English

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publication date

November 2012

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published in

Traffic

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volume

13

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issue

11

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page(s)

1457-65

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cites work

Plasmodium falciparum signal peptide peptidase is a promising drug target against blood stage malaria

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27 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-0854.2012.01402.X

Induction and localization of Plasmodium falciparum stress proteins related to the heat shock protein 70 family

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Invasion by Toxoplasma gondii establishes a moving junction that selectively excludes host cell plasma membrane proteins on the basis of their membrane anchoring

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Proteolytic digestion of band 3 at an external site alters the erythrocyte membrane organisation and may facilitate malarial invasion

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27 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-0854.2012.01402.X

Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites

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27 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-0854.2012.01402.X

Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte

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https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-0854.2012.01402.X

A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin

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27 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-0854.2012.01402.X

Identification of signal peptide peptidase, a presenilin-type aspartic protease

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27 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-0854.2012.01402.X

Targeting presenilin-type aspartic protease signal peptide peptidase with gamma-secretase inhibitors

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Plasmodium falciparum signal sequences: simply sequences or special signals?

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Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites

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Pfsbp1, a Maurer's cleft Plasmodium falciparum protein, is associated with the erythrocyte skeleton

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Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3

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Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1

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A small molecule inhibitor of signal peptide peptidase inhibits Plasmodium development in the liver and decreases malaria severity

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27 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1600-0854.2012.01402.X

Localization of organellar proteins in Plasmodium falciparum using a novel set of transfection vectors and a new immunofluorescence fixation method

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Isolation and characterization of type I signal peptidase of different malaria parasites

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Erythrocyte entry by malarial parasites. A moving junction between erythrocyte and parasite

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Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase

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Invasion of erythrocytes by malaria merozoites

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The role of ankyrin in shape and deformability change of human erythrocyte ghosts

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Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine protease inhibitor

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27 May 2022

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A genome-wide chromatin-associated nuclear peroxiredoxin from the malaria parasite Plasmodium falciparum

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Interactions with heparin-like molecules during erythrocyte invasion by Plasmodium falciparum merozoites

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Ovalocytosis and cerebral malaria

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Plasmodium falciparum signal peptidase is regulated by phosphorylation and required for intra-erythrocytic growth

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A repetitive antigen of Plasmodium falciparum that is homologous to heat shock protein 70 of Drosophila melanogaster

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Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

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Development of fluorescent Plasmodium falciparum for in vitro growth inhibition assays

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Cytoskeletal and membrane remodelling during malaria parasite invasion of the human erythrocyte

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Identification of an endoplasmic reticulum-resident calcium-binding protein with multiple EF-hand motifs in asexual stages of Plasmodium falciparum

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A Presenilin-like protease associated with Plasmodium falciparum micronemes is involved in erythrocyte invasion

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Reticulocyte binding protein homologues are key adhesins during erythrocyte invasion by Plasmodium falciparum

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Skeleton-binding protein 1 functions at the parasitophorous vacuole membrane to traffic PfEMP1 to the Plasmodium falciparum-infected erythrocyte surface

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Secretase targets for Alzheimer's disease: identification and therapeutic potential

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Band 3 multiprotein complexes in the red cell membrane; of mice and men.

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Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors

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Colocalization analysis in fluorescence micrographs: verification of a more accurate calculation of pearson's correlation coefficient.

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Identifiers

DOI

10.1111/J.1600-0854.2012.01402.X

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PubMed publication ID

22844982

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ResearchGate publication ID

230587215

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(Q27976475)

Malaria parasite signal peptide peptidase is an ER-resident protease required for growth but not for invasion

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