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Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS
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PubMed
review article
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Europe PubMed Central
title
Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS
(English)
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stated in
PubMed
main subject
microglia
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pathogenesis
1 reference
based on heuristic
inferred from title
astrocyte
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amyotrophic lateral sclerosis
1 reference
based on heuristic
inferred from title
author name string
Junghee Lee
series ordinal
1
1 reference
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Crossref
Seung Jae Hyeon
series ordinal
2
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Crossref
Hyeonjoo Im
series ordinal
3
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Crossref
Hyun Ryu
series ordinal
4
1 reference
stated in
Crossref
Yunha Kim
series ordinal
5
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Hoon Ryu
series ordinal
6
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Crossref
language of work or name
English
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PubMed
publication date
October 2016
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PubMed
published in
Experimental neurobiology
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stated in
PubMed
volume
25
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PubMed
issue
5
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stated in
PubMed
page(s)
233-240
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stated in
PubMed
copyright license
Creative Commons Attribution-NonCommercial 4.0 International
start time
31 October 2016
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April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Microglia centered pathogenesis in ALS: insights in cell interconnectivity
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PubMed Central
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Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis
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A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
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Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
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PubMed Central
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Jean-Martin Charcot: The Father of Neurology
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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
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From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
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Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
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20 March 2017
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
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TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
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PubMed Central
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Amyotrophic lateral sclerosis
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PubMed Central
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7 April 2017
Genetic dys-regulation of astrocytic glutamate transporter EAAT2 and its implications in neurological disorders and manganese toxicity
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PubMed Central
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29 September 2017
Therapeutic targeting of epigenetic components in amyotrophic lateral sclerosis (ALS).
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29 September 2017
Astrogliosis is a possible player in preventing delayed neuronal death
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PubMed Central
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29 September 2017
Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
The changing scene of amyotrophic lateral sclerosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Motor neuron impairment mediated by a sumoylated fragment of the glial glutamate transporter EAAT2
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PubMed Central
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29 September 2017
Differential expression of c-Ret in motor neurons versus non-neuronal cells is linked to the pathogenesis of ALS.
1 reference
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PubMed Central
reference URL
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29 September 2017
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Differential regulation of neuronal and inducible nitric oxide synthase (NOS) in the spinal cord of mutant SOD1 (G93A) ALS mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Motor neuronal protection by L-arginine prolongs survival of mutant SOD1 (G93A) ALS mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis
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PubMed Central
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29 September 2017
Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: the GENEVA study. Rationale, study design and demographic characteristics.
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PubMed Central
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29 September 2017
Neuroinflammation and regulation of glial glutamate uptake in neurological disorders
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
On the relation of oxidative stress to neuroinflammation: lessons learned from the G93A-SOD1 mouse model of amyotrophic lateral sclerosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Actions of TNF-alpha on glutamatergic synaptic transmission in the central nervous system
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Prospects for the pharmacotherapy of amyotrophic lateral sclerosis : old strategies and new paradigms for the third millennium
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Inflammatory processes in amyotrophic lateral sclerosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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29 September 2017
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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2 June 2018
NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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27 November 2018
Neurodegenerative disease: C9orf72 RNA foci--a therapeutic target for ALS and FTD?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Expression of taurine transporter (TauT) is modulated by heat shock factor 1 (HSF1) in motor neurons of ALS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Selective up-regulation of the glial Na+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Oxidative damage to proteins in the spinal cord in amyotrophic lateral sclerosis (ALS).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Reduced expression of glutamate transporter EAAT2 and impaired glutamate transport in human primary astrocytes exposed to HIV-1 or gp120.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Oxidative damage to mitochondrial DNA in spinal motoneurons of transgenic ALS mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
retrieved
27 November 2018
Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5081469
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27 November 2018
Loss of the astrocyte glutamate transporter GLT1 modifies disease in SOD1(G93A) mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27790057
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
[ALS and microglia--a player for non-cell-autonomous neuron death]
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27790057
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27790057
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Of mice and men: reconciling preclinical ALS mouse studies and human clinical trials
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27790057
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27790057
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.5607/EN.2016.25.5.233
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2878383
OpenCitations bibliographic resource ID
2878383
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2878383
PMC publication ID
5081469
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2878383
PubMed publication ID
27790057
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2878383
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