(Q53413551)

14 May 2018

title

NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients. (English)

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14 May 2018

amyotrophic lateral sclerosis

main subject

patient

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astrocyte

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1 reference

1 reference

Sonja Johann

1

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14 May 2018

Marius Heitzer

2

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14 May 2018

Mithila Kanagaratnam

3

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14 May 2018

Anand Goswami

4

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14 May 2018

Tania Rizo

5

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14 May 2018

Joachim Weis

6

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14 May 2018

Dirk Troost

7

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14 May 2018

Cordian Beyer

8

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14 May 2018

publication date

21 July 2015

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14 May 2018

published in

Glia

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14 May 2018

volume

63

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14 May 2018

issue

12

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14 May 2018

page(s)

2260-2273

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14 May 2018

Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations

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Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis

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A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

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Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

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Immune function of astrocytes

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Inflammation and neurovascular changes in amyotrophic lateral sclerosis.

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Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis.

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Mechanisms underlying inflammation in neurodegeneration

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Accumulation of STIM1 is associated with the degenerative muscle fibre phenotype in ALS and other neurogenic atrophies.

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7 January 2021

Transgenic-mouse model of amyotrophic lateral sclerosis

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7 January 2021

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

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7 January 2021

Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS.

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7 January 2021

Innate immune activation in neurodegenerative disease

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7 January 2021

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

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7 January 2021

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

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7 January 2021

Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology

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7 January 2021

Evaluating the levels of interleukin-1 family cytokines in sporadic amyotrophic lateral sclerosis.

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7 January 2021

Interleukin-18 expression after focal ischemia of the rat brain: association with the late-stage inflammatory response.

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The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18.

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7 January 2021

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

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7 January 2021

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

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7 January 2021

Amyotrophic lateral sclerosis

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7 January 2021

Oestrogen and progesterone reduce lipopolysaccharide-induced expression of tumour necrosis factor-alpha and interleukin-18 in midbrain astrocytes

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7 January 2021

Sensing damage by the NLRP3 inflammasome

1 reference

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7 January 2021

Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS)

1 reference

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7 January 2021

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

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7 January 2021

Differentiated NSC-34 motoneuron-like cells as experimental model for cholinergic neurodegeneration

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7 January 2021

Cryopyrin activates the inflammasome in response to toxins and ATP

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7 January 2021

Signaling by ROS drives inflammasome activation

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7 January 2021

Gout-associated uric acid crystals activate the NALP3 inflammasome

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7 January 2021

Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis.

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7 January 2021

Innate immunity in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Increased mitochondrial oxidative damage and oxidative DNA damage contributes to the neurodegenerative process in sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Regulation of inflammasome signaling

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

https://api.crossref.org/works/10.1002%2FGLIA.22891

1 reference

7 January 2021

Global quantification of mammalian gene expression control

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7 January 2021

Design, power, and interpretation of studies in the standard murine model of ALS

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Astrocytes: biology and pathology

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7 January 2021

PAMPs and DAMPs: signal 0s that spur autophagy and immunity

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https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Mechanisms, models and biomarkers in amyotrophic lateral sclerosis

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7 January 2021

Inflammatory cytokine release of astrocytes in vitro is reduced by all-trans retinoic acid

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7 January 2021

Astrogliosis in amyotrophic lateral sclerosis: role and therapeutic potential of astrocytes

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https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22891

7 January 2021

Identifiers

DOI

10.1002/GLIA.22891

1 reference

14 May 2018

PubMed ID

26200799

1 reference

14 May 2018