(Q37959310)

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Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 August 2017

Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology (English)

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Europe PubMed Central

PubMed publication ID

25 August 2017

amyotrophic lateral sclerosis

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object named as

Janine Kirby

3

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Michael J Strong

object named as

Michael J Strong

6

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object named as

Pamela J Shaw

7

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author name string

Paul G Ince

1

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

J Robin Highley

2

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Europe PubMed Central

PubMed publication ID

25 August 2017

Stephen B Wharton

4

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

Hitoshi Takahashi

5

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Europe PubMed Central

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25 August 2017

language of work or name

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based on heuristic

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publication date

22 November 2011

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Europe PubMed Central

PubMed publication ID

25 August 2017

Acta Neuropathologica

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Europe PubMed Central

PubMed publication ID

25 August 2017

122

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Europe PubMed Central

PubMed publication ID

25 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

657-671

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

https://scigraph.springernature.com/pub.10.1007/s00401-011-0913-0

0 references

A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

An estimate of amyotrophic lateral sclerosis heritability using twin data.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Amyotrophic lateral sclerosis associated with mutations in the CuZn superoxide dismutase gene

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Stress granules: the Tao of RNA triage

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Glial proliferation and metabotropic glutamate receptor expression in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Glial cells of the spinal cord and subcortical white matter up-regulate neuronal nitric oxide synthase in sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 regulates its mRNA levels through a negative feedback loop

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Structural determinants of the cellular localization and shuttling of TDP-43.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Astrocyte function and role in motor neuron disease: a future therapeutic target?

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Mutation within TARDBP leads to frontotemporal dementia without motor neuron disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Motor neuron disease in a patient with a mitochondrial tRNAIle mutation

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Astrocytic degeneration relates to the severity of disease in frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Nuclear factor TDP-43 can affect selected microRNA levels

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

A de novo missense mutation of the FUS gene in a "true" sporadic ALS case

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Proliferative potential of human astrocytes.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 is recruited to stress granules in conditions of oxidative insult.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Limited corticospinal tract involvement in amyotrophic lateral sclerosis subjects with the A4V mutation in the copper/zinc superoxide dismutase gene.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Whole-genome analysis of sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Communication between neurons and astrocytes: relevance to the modulation of synaptic and network activity

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS).

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Novel FUS/TLS mutations and pathology in familial and sporadic amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Amyotrophic lateral sclerosis: current issues in classification, pathogenesis and molecular pathology

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Amyotrophic lateral sclerosis associated with genetic abnormalities in the gene encoding Cu/Zn superoxide dismutase: molecular pathology of five new cases, and comparison with previous reports and 73 sporadic cases of ALS.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Exome sequencing reveals VCP mutations as a cause of familial ALS

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

alpha-Synucleinopathy models and human neuropathology: similarities and differences

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

No evidence for cognitive dysfunction or depression in patients with mild restless legs syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

A pathogenic peripherin gene mutation in a patient with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: two distinct patterns correlating with disease severity and mutation

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Expression and localization of cyclooxygenase‐1 and ‐2 in human sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Mutations of optineurin in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Glial cell inclusions and the pathogenesis of neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL-/- mice: support for a role for TDP-43 in the physiological response to neuronal injury.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Reactive astrocytes are widespread in the cortical gray matter of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Progressive loss of motor neuron function in wasted mice: effects of a spontaneous null mutation in the gene for the eEF1 A2 translation factor

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Long-range intracortical excitation shapes olfactory processing.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 is a developmentally regulated protein essential for early embryonic development

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 dimerizes in human cells in culture.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Evidence for a common pathway linking neurodegenerative diseases.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Progressive motor weakness in transgenic mice expressing human TDP-43.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

The pathobiology of amyotrophic lateral sclerosis: a proteinopathy?

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Genetic contribution of FUS to frontotemporal lobar degeneration

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Astrogliosis in amyotrophic lateral sclerosis: role and therapeutic potential of astrocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Astrocytes in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Astrocytes, from brain glue to communication elements: the revolution continues

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Microtubule-associated tau protein positive neuronal and glial inclusions in ALS.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

A novel mutation (K317M) in the MAPT gene causes FTDP and motor neuron disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Transgenic rat model of neurodegeneration caused by mutation in the TDP gene.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

TDP-43 physically interacts with amyotrophic lateral sclerosis-linked mutant CuZn superoxide dismutase

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

?True? sporadic ALS associated with a novel SOD-1 mutation

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Analysis of chromosome 5q13 genes in amyotrophic lateral sclerosis: Homozygous naip deletion in a sporadic case

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0913-0

21 January 2018

Identifiers

10.1007/S00401-011-0913-0

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 August 2017

ResearchGate publication ID

0 references

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