(Q28080830)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25966814%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

review article

1 reference

title

Concise Review: CXCR4/CXCL12 Signaling in Immature Hematopoiesis--Lessons From Pharmacological and Genetic Models (English)

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25966814%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25966814%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

author name string

Darja Karpova

series ordinal

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25966814%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

language of work or name

1 reference

25 May 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25966814%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25966814%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

volume

33

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25966814%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

issue

8

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25966814%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

page(s)

2391-2399

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25966814%20AND%20SRC:MED&resulttype=core&format=json

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors

8 March 2020

cites work

1 reference

The chemokine and chemokine receptor superfamilies and their molecular evolution

21 January 2018

1 reference

CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin

21 January 2018

1 reference

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

21 January 2018

1 reference

Identification of a major co-receptor for primary isolates of HIV-1

21 January 2018

1 reference

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

21 January 2018

1 reference

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

21 January 2018

1 reference

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

21 January 2018

1 reference

Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin

21 January 2018

1 reference

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

21 January 2018

1 reference

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

21 January 2018

1 reference

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

21 January 2018

1 reference

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

21 January 2018

1 reference

A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor

21 January 2018

1 reference

The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival

21 January 2018

1 reference

Macrophage migration inhibitory factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of cancer-associated fibroblasts

21 January 2018

1 reference

Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines

21 January 2018

1 reference

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

21 January 2018

1 reference

Hematopoietic stem cells are uniquely selective in their migratory response to chemokines

21 January 2018

1 reference

CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice

21 January 2018

1 reference

The IKKα-dependent NF-κB p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1.

21 January 2018

1 reference

Pertussis toxin inhibits migration of B and T lymphocytes into splenic white pulp cords

21 January 2018

1 reference

The molecular biology of leukocyte chemoattractant receptors

21 January 2018

1 reference

The role of G-protein signaling in hematopoietic stem/progenitor cell mobilization.

21 January 2018

1 reference

PTX-sensitive signals in bone marrow homing of fetal and adult hematopoietic progenitor cells

21 January 2018

1 reference

Hierarchy of molecular-pathway usage in bone marrow homing and its shift by cytokines.

21 January 2018

1 reference

SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury

21 January 2018

1 reference

On the adaptation of endosteal stem cell niche function in response to stress.

21 January 2018

1 reference

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

21 January 2018

1 reference

Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4-/- chimeric mice.

21 January 2018

1 reference

CXCR4 is required for the quiescence of primitive hematopoietic cells

21 January 2018

1 reference

Chromothriptic cure of WHIM syndrome

21 January 2018

1 reference

Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches

21 January 2018

1 reference

Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression

21 January 2018

1 reference

VCAM-1 ablation in nonhematopoietic cells in MxCre+ VCAM-1f/f mice is variable and dictates their phenotype

21 January 2018

1 reference

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

21 January 2018

1 reference

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

21 January 2018

1 reference

Regulation of CXCR4 signaling

21 January 2018

1 reference

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor.

21 January 2018

1 reference

Functional consequences of perturbed CXCL12 signal processing: analyses of immature hematopoiesis in GRK6-deficient mice

21 January 2018

1 reference

WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4

21 January 2018

1 reference

Stage-specific roles for CXCR4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation

21 January 2018

1 reference

Hematopoietic stem cell mobilization: updated conceptual renditions

21 January 2018

1 reference

Concise review: Sowing the seeds of a fruitful harvest: hematopoietic stem cell mobilization

21 January 2018

1 reference

Advances in stem cell mobilization

21 January 2018

1 reference

A novel perspective on stem cell homing and mobilization: review on bioactive lipids as potent chemoattractants and cationic peptides as underappreciated modulators of responsiveness to SDF-1 gradients

21 January 2018

1 reference

Insights into the biology of mobilized hematopoietic stem/progenitor cells through innovative treatment schedules of the CXCR4 antagonist AMD3100.

21 January 2018

1 reference

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist

21 January 2018

1 reference

Concurrent blockade of alpha4-integrin and CXCR4 in hematopoietic stem/progenitor cell mobilization

21 January 2018

1 reference

BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells.

21 January 2018

1 reference

CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow

21 January 2018

1 reference

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

21 January 2018

1 reference

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

21 January 2018

1 reference

Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation.

21 January 2018

1 reference

Mechanisms of G-CSF-mediated hematopoietic stem and progenitor mobilization

21 January 2018

1 reference

Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide

21 January 2018

1 reference

CXCR7 protein is not expressed on human or mouse leukocytes

21 January 2018

1 reference

Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

21 January 2018

1 reference

Imaging ligand-dependent activation of CXCR7.

21 January 2018

1 reference

CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons.

21 January 2018

1 reference

Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells

21 January 2018

1 reference

Endothelial expression of CXCR7 and the regulation of systemic CXCL12 levels.

21 January 2018

1 reference

Generation and dynamics of an endogenous, self-generated signaling gradient across a migrating tissue

21 January 2018

1 reference

Hematopoietic progenitor cells (HPC) from mobilized peripheral blood display enhanced migration and marrow homing compared to steady-state bone marrow HPC.

21 January 2018

1 reference

Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice

21 January 2018

1 reference

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

21 January 2018

1 reference

CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity

21 January 2018

1 reference

An infernal trio: the chemokine CXCL12 and its receptors CXCR4 and CXCR7 in tumor biology.

21 January 2018

1 reference

The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects

21 January 2018

1 reference

Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection

21 January 2018

1 reference

HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication

21 January 2018

1 reference

Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection.

21 January 2018

1 reference

Enhanced unique pattern of hematopoietic cell mobilization induced by the CXCR4 antagonist 4F-benzoyl-TN14003.

21 January 2018

1 reference

The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34+ cells in patients with multiple myeloma

21 January 2018

1 reference

Discovery of novel, highly potent and selective beta-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles

21 January 2018

1 reference

Discovery and characterization of an endogenous CXCR4 antagonist

21 January 2018

1 reference

CXCL14 antagonizes the CXCL12-CXCR4 signaling axis

21 January 2018

1 reference

CXCL14 is a natural inhibitor of the CXCL12-CXCR4 signaling axis.

21 January 2018

1 reference

Dimeric peptides of the C-terminal region of CXCL14 function as CXCL12 inhibitors

21 January 2018

1 reference

CXCL14 is no direct modulator of CXCR4.

21 January 2018

1 reference

Nice neighborhood: emerging concepts of the stem cell niche

21 January 2018

1 reference

The leukemic stem cell niche: current concepts and therapeutic opportunities

21 January 2018

1 reference

Combination of imatinib with CXCR4 antagonist BKT140 overcomes the protective effect of stroma and targets CML in vitro and in vivo

21 January 2018

1 reference

CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growth

21 January 2018

1 reference

A review on CXCR4/CXCL12 axis in oncology: no place to hide.

21 January 2018

1 reference

WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12

21 January 2018

1 reference