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Analysis of genetic variation and potential applications in genome-scale metabolic modeling
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title
Analysis of genetic variation and potential applications in genome-scale metabolic modeling
(English)
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PubMed
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genetic variation
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author
João Cardoso
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1
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4329917
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25763369%20AND%20SRC:MED&resulttype=core&format=json
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5 June 2020
Mikael Rørdam Andersen
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2
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Europe PubMed Central
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4329917
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25763369%20AND%20SRC:MED&resulttype=core&format=json
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5 June 2020
Nikolaus Sonnenschein
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4329917
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25763369%20AND%20SRC:MED&resulttype=core&format=json
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5 June 2020
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Markus J Herrgård
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4329917
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5 June 2020
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English
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16 February 2015
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Frontiers in Bioengineering and Biotechnology
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Europe PubMed Central
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4329917
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5 June 2020
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3
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Europe PubMed Central
PMC publication ID
4329917
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25763369%20AND%20SRC:MED&resulttype=core&format=json
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5 June 2020
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13
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4329917
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5 June 2020
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
Multiple high-throughput analyses monitor the response of E. coli to perturbations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
Predicting the insurgence of human genetic diseases associated to single point protein mutations with support vector machines and evolutionary information
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
Systems biology of SNPs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
SNPs3D: candidate gene and SNP selection for association studies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
Comprehensive statistical study of 452 BRCA1 missense substitutions with classification of eight recurrent substitutions as neutral
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
LS-SNP: large-scale annotation of coding non-synonymous SNPs based on multiple information sources.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
Coding single-nucleotide polymorphisms associated with complex vs. Mendelian disease: evolutionary evidence for differences in molecular effects.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
Integrating high-throughput and computational data elucidates bacterial networks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
A comparative study of machine-learning methods to predict the effects of single nucleotide polymorphisms on protein function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
In silico model-driven assessment of the effects of single nucleotide polymorphisms (SNPs) on human red blood cell metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
29 September 2017
VarMod: modelling the functional effects of non-synonymous variants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
2 June 2018
Predicting the functional, molecular, and phenotypic consequences of amino acid substitutions using hidden Markov models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
2 June 2018
RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
2 June 2018
Predicting metabolic engineering knockout strategies for chemical production: accounting for competing pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
2 June 2018
Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
2 June 2018
PMUT: a web-based tool for the annotation of pathological mutations on proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
2 June 2018
A kinetic model for curcumin production in Escherichia coli.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Genetics. Predicting microbial growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
MutationTaster2: mutation prediction for the deep-sequencing age.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Kinetic modelling of central carbon metabolism in Escherichia coli
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Predicting phenotypic variation in yeast from individual genome sequences.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Hansa: an automated method for discriminating disease and neutral human nsSNPs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Statistical geometry based prediction of nonsynonymous SNP functional effects using random forest and neuro-fuzzy classifiers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Dynamic modeling of the central carbon metabolism of Escherichia coli.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Finding new structural and sequence attributes to predict possible disease association of single amino acid polymorphism (SAP).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Evaluation of structural and evolutionary contributions to deleterious mutation prediction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Assessing the relative importance of the biophysical properties of amino acid substitutions associated with human genetic disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4329917
retrieved
27 November 2018
Performance of mutation pathogenicity prediction methods on missense variants
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25763369
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Large-scale analysis of non-synonymous coding region single nucleotide polymorphisms
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25763369
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FBIOE.2015.00013
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3116898
stated in
Europe PubMed Central
PMC publication ID
4329917
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25763369%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
OpenCitations bibliographic resource ID
3116898
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3116898
PMC publication ID
4329917
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3116898
stated in
Europe PubMed Central
PMC publication ID
4329917
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25763369%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
PubMed publication ID
25763369
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3116898
stated in
Europe PubMed Central
PMC publication ID
4329917
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25763369%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
ResearchGate publication ID
272676315
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