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Transcriptional Regulatory Circuits Controlling Brown Fat Development and Activation
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11 October 2019
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12 October 2019
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19 January 2021
title
Transcriptional Regulatory Circuits Controlling Brown Fat Development and Activation
(English)
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PubMed
main subject
tissue
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PubMed
retrieved
11 October 2019
cell
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12 October 2019
transcription
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PubMed
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19 January 2021
author name string
Patrick Seale
series ordinal
1
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language of work or name
English
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publication date
July 2015
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PubMed
1 July 2015
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PubMed Central
retrieved
11 October 2019
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PubMed Central
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12 October 2019
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PubMed Central
retrieved
19 January 2021
published in
Diabetes
4 references
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PubMed
stated in
PubMed Central
retrieved
11 October 2019
stated in
PubMed Central
retrieved
12 October 2019
stated in
PubMed Central
retrieved
19 January 2021
volume
64
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PubMed
issue
7
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PubMed
page(s)
2369-75
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cites work
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Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice
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miR-133a regulates adipocyte browning in vivo
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PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.
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Thermogenic activity of UCP1 in human white fat-derived beige adipocytes
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PPARα and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders
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29 September 2017
A multifunctional protein, EWS, is essential for early brown fat lineage determination
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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
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Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.
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Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
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Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic [...]
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29 September 2017
C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists
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Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade
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Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
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Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone
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Peroxisome proliferator-activated receptor gamma agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice.
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29 September 2017
p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene
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29 September 2017
Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone
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29 September 2017
Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation.
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29 September 2017
Thiazolidinediones inhibit the expression of beta3-adrenergic receptors at a transcriptional level
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29 September 2017
Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity
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29 September 2017
Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity
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29 September 2017
Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor gamma
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2 June 2018
Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene expression
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2 June 2018
PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.
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Acquirement of brown fat cell features by human white adipocytes
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2 June 2018
Myocardin-related transcription factor A regulates conversion of progenitors to beige adipocytes
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27 November 2018
Fenofibrate (PPARalpha agonist) induces beige cell formation in subcutaneous white adipose tissue from diet-induced male obese mice.
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27 November 2018
The PPARgamma agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake
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27 November 2018
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27 November 2018
Peroxisome proliferator-activated receptor-gamma-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status
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27 November 2018
Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone.
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27 November 2018
Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell.
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27 November 2018
A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice
1 reference
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reference URL
https://pubmed.ncbi.nlm.nih.gov/26050669
retrieved
12 December 2020
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Identifiers
DOI
10.2337/DB15-0203
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
661175
OpenCitations bibliographic resource ID
661175
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
661175
PMC publication ID
4477361
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
661175
PubMed publication ID
26050669
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
661175
ResearchGate publication ID
277894577
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