(Q34089543)

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Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic [...]

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15 January 2020

Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes (English)

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15 January 2020

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Irina G. Shabalina

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15 January 2020

James A Timmons

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15 January 2020

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15 January 2020

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15 January 2020

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Tomas B Walden

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15 January 2020

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Natasa Petrovic

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15 January 2020

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22 December 2009

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15 January 2020

Journal of Biological Chemistry

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15 January 2020

285

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15 January 2020

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15 January 2020

7153-7164

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15 January 2020

Transdifferentiation properties of adipocytes in the adipose organ

1 reference

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5 July 2018

The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue.

1 reference

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5 July 2018

High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Functional brown adipose tissue in healthy adults

1 reference

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5 July 2018

Identification and importance of brown adipose tissue in adult humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Cold-activated brown adipose tissue in healthy men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Transcriptional control of brown adipocyte development and physiological function--of mice and men.

1 reference

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5 July 2018

UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Distinct expression of muscle-specific microRNAs (myomirs) in brown adipocytes.

1 reference

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5 July 2018

White fat progenitor cells reside in the adipose vasculature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

PRDM16 controls a brown fat/skeletal muscle switch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Molecular determinants of brown adipocyte formation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

MicroRNA-206: the skeletal muscle-specific myomiR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Transcriptional control of brown fat determination by PRDM16

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Unexpected evidence for active brown adipose tissue in adult humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Evidence for a role of developmental genes in the origin of obesity and body fat distribution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

A human-specific role of cell death-inducing DFFA (DNA fragmentation factor-alpha)-like effector A (CIDEA) in adipocyte lipolysis and obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Nuclear receptor corepressor RIP140 regulates fat accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Peroxisome proliferator-activated receptor gamma agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Brown adipose tissue: function and physiological significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Cidea-deficient mice have lean phenotype and are resistant to obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Acquirement of brown fat cell features by human white adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Peroxisome proliferator-activated receptors: nuclear control of metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Cig30, a mouse member of a novel membrane protein gene family, is involved in the recruitment of brown adipose tissue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Expression of a cDNA isolated from rat brown adipose tissue and heart identifies the product as the muscle isoform of carnitine palmitoyltransferase I (M-CPT I). M-CPT I is the predominant CPT I isoform expressed in both white (epididymal) and brown

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

5 July 2018

Developmental biology: Neither fat nor flesh.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

A reservoir of brown adipocyte progenitors in human skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Within brown-fat cells, UCP1-mediated fatty acid-induced uncoupling is independent of fatty acid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

PPAR-gamma activation mediates adipose depot-specific effects on gene expression and lipoprotein lipase activity: mechanisms for modulation of postprandial lipemia and differential adipose accretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Emergence during development of the white-adipocyte cell phenotype is independent of the brown-adipocyte cell phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Thermogenic responses in brown fat cells are fully UCP1-dependent. UCP2 or UCP3 do not substitute for UCP1 in adrenergically or fatty scid-induced thermogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Induction and degradation of the uncoupling protein thermogenin in brown adipocytes in vitro and in vivo. Evidence for a rapidly degradable pool.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844165

28 October 2018

A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in interscapular brown adipose tissue of the rat during perinatal and early postnatal development and after cold acclimation. II. Mitochondrial changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of brown fat cells in monolayer culture. I. Morphological and biochemical distinction from white fat cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epididymal white adipose tissue after cold stress in rats. I. Nonmitochondrial changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic and cellular plasticity in white adipose tissue II: role of peroxisome proliferator-activated receptor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UCP1 is essential for adaptive adrenergic nonshivering thermogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028987

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.053942

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20028987%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20028987%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20028987%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

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