(Q28116404)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Role of defensins in corneal epithelial barrier function against Pseudomonas aeruginosa traversal (English)

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

main subject

Pseudomonas aeruginosa

0 references

Defensin beta 4B

1 reference

Defensin beta 1

1 reference

Defensin beta 103A

1 reference

Cathelicidin antimicrobial peptide

1 reference

defense response to bacterium

1 reference

Defensin beta 1

1 reference

Defensin beta 3

1 reference

Cathelicidin antimicrobial peptide

1 reference

Defensin beta 4

1 reference

Defensin beta 14

1 reference

author

David J Evans

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Suzanne Fleiszig

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

3

Connie Tam

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1

Danielle K Augustin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2

Susan R Heimer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Wing Y Li

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Jeff M Le Due

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

29 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

published in

Infection and Immunity

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

79

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

595-605

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

2

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

Rhamnolipids are virulence factors that promote early infiltration of primary human airway epithelia by Pseudomonas aeruginosa

17 January 2020

cites work

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

20 March 2017

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Defensins: antimicrobial peptides of innate immunity

20 March 2017

1 reference

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Factors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal

20 March 2017

1 reference

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Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection

29 September 2017

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Flagellin stimulates protective lung mucosal immunity: role of cathelicidin-related antimicrobial peptide

29 September 2017

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Flagellin-induced corneal antimicrobial peptide production and wound repair involve a novel NF-kappaB-independent and EGFR-dependent pathway

29 September 2017

1 reference

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The impact of inoculation parameters on the pathogenesis of contact lens-related infectious keratitis.

29 September 2017

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Role of the corneal epithelial basement membrane in ocular defense against Pseudomonas aeruginosa.

29 September 2017

1 reference

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Epidemiological characteristics, predisposing factors and microbiological profiles of infectious corneal ulcers: the Portsmouth corneal ulcer study

29 September 2017

1 reference

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The role of twitching motility in Pseudomonas aeruginosa exit from and translocation of corneal epithelial cells

29 September 2017

1 reference

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The role of antimicrobial peptides at the ocular surface

29 September 2017

1 reference

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Toll-like receptors at the ocular surface

29 September 2017

1 reference

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Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa.

29 September 2017

1 reference

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Expression and secretion of cathelicidin LL-37 in human epithelial cells after infection by Mycobacterium bovis Bacillus Calmette-Guérin

29 September 2017

1 reference

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The type III toxins of Pseudomonas aeruginosa disrupt epithelial barrier function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Ocular surface expression and in vitro activity of antimicrobial peptides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Defensins in the immunology of bacterial infections

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Life at the front: dissecting bacterial-host interactions at the ocular surface.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

LPS-induced mucin expression in human sinus mucosa can be attenuated by hCLCA inhibitors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Pulmonary collectins in innate immunity of the lung

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Pseudomonas aeruginosa exploits a PIP3-dependent pathway to transform apical into basolateral membrane

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Human tear fluid protects against Pseudomonas aeruginosa keratitis in a murine experimental model.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

The suprabasal layer of corneal epithelial cells represents the major barrier site to the passive movement of small molecules and trafficking leukocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Antimicrobial peptides in the airway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Surfactant protein D is present in human tear fluid and the cornea and inhibits epithelial cell invasion by Pseudomonas aeruginosa

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Characterization of growth and differentiation in a telomerase-immortalized human corneal epithelial cell line.

29 September 2017

1 reference

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Corneal response to Pseudomonas aeruginosa infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Role of mucins in the function of the corneal and conjunctival epithelia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Surfactant proteins A and D inhibit the growth of Gram-negative bacteria by increasing membrane permeability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Defensin Expression by the Cornea: Multiple Signalling Pathways Mediate IL-1β Stimulation of hBD-2 Expression by Human Corneal Epithelial Cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Protection against fatal Pseudomonas aeruginosa pneumonia in mice after nasal immunization with a live, attenuated aroA deletion mutant

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Signaling networks controlling mucin production in response to Gram-positive and Gram-negative bacteria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Interaction of bacterial pathogens with polarized epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Penetration of clinical isolates of Pseudomonas aeruginosa through MDCK epithelial cell monolayers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Susceptibility of epithelial cells to Pseudomonas aeruginosa invasion and cytotoxicity is upregulated by hepatocyte growth factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Epithelial cell polarity affects susceptibility to Pseudomonas aeruginosa invasion and cytotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

A bacterial protease perturbs the paracellular barrier function of transporting epithelial monolayers in culture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Modulation of Pseudomonas aeruginosa adherence to the corneal surface by mucus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Clearance of Pseudomonas aeruginosa from a healthy ocular surface involves surfactant protein D and is compromised by bacterial elastase in a murine null-infection model.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

In vitro activity of human beta-defensin 2 against Pseudomonas aeruginosa in the presence of tear fluid

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Ocular surface epithelia express mRNA for human beta defensin-2.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Pseudomonas aeruginosa and epithelial permeability: role of virulence factors elastase and exotoxin A.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Gene expression of human beta-defensins in healthy and inflamed human dental pulps.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

The incidence of contact lens-related microbial keratitis in Australia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Exposure of human corneal epithelial cells to contact lenses in vitro suppresses the upregulation of human beta-defensin-2 in response to antigens of Pseudomonas aeruginosa.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Role of Pseudomonas aeruginosa ExsA in penetration through corneal epithelium in a novel in vivo model.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Contribution of ExsA-regulated factors to corneal infection by cytotoxic and invasive Pseudomonas aeruginosa in a murine scarification model.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3028852

Secretory IgA inhibits Pseudomonas aeruginosa binding to cornea and protects against keratitis

27 November 2018

1 reference

12 December 2020

Synergistic actions of antibacterial neutrophil defensins and cathelicidins

1 reference

12 December 2020

Toll-like receptor signaling pathways

1 reference

12 December 2020

Beta-defensins 2 and 3 together promote resistance to Pseudomonas aeruginosa keratitis

1 reference

12 December 2020

Identifiers

DOI

10.1128/IAI.00854-10

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21115716%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2 references