(Q28117783)

4 January 2017

title

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides (English)

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4 January 2017

Tomo Saric

1

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4 January 2017

Shih-Chung Chang

2

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4 January 2017

Akira Hattori

3

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4 January 2017

Ian A. York

4

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4 January 2017

Shirley Markant

5

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4 January 2017

Kenneth L. Rock

6

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4 January 2017

Masafumi Tsujimoto

7

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4 January 2017

Alfred L. Goldberg

8

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4 January 2017

language of work or name

English

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publication date

1 December 2002

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4 January 2017

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4 January 2017

volume

3

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4 January 2017

issue

12

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4 January 2017

page(s)

1169–1176

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

4 January 2017

cites work

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7 January 2021

The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells

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7 January 2021

Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation

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7 January 2021

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

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7 January 2021

The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.

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7 January 2021

Degradation of cell proteins and the generation of MHC class I-presented peptides

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7 January 2021

Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide

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7 January 2021

Cytotoxic T lymphocyte epitopes of HIV-1 Nef: Generation of multiple definitive major histocompatibility complex class I ligands by proteasomes

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7 January 2021

26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide

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7 January 2021

Discrete proteolytic intermediates in the MHC class I antigen processing pathway and MHC I-dependent peptide trimming in the ER.

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7 January 2021

ER aminopeptidases generate a unique pool of peptides for MHC class I molecules.

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7 January 2021

The murine cytomegalovirus pp89 immunodominant H-2Ld epitope is generated and translocated into the endoplasmic reticulum as an 11-mer precursor peptide

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7 January 2021

Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase

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7 January 2021

Two new proteases in the MHC class I processing pathway

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7 January 2021

Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

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7 January 2021

Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.

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7 January 2021

Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-gamma-induced subunits LMP2 and LMP7.

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7 January 2021

Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells

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7 January 2021

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase

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7 January 2021

Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum

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7 January 2021

Proteolytic processing of peptides in the lumen of the endoplasmic reticulum for antigen presentation by major histocompatibility class I

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7 January 2021

Trimming of antigenic peptides in an early secretory compartment

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7 January 2021

Efficient MHC class I-independent amino-terminal trimming of epitope precursor peptides in the endoplasmic reticulum

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7 January 2021

MHC class I molecules can direct proteolytic cleavage of antigenic precursors in the endoplasmic reticulum

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7 January 2021

A role for a novel luminal endoplasmic reticulum aminopeptidase in final trimming of 26 S proteasome-generated major histocompatability complex class I antigenic peptides

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7 January 2021

Signal Sequence Processing in Rough Microsomes

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7 January 2021

Cellular peptide composition governed by major histocompatibility complex class I molecules.

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7 January 2021

An endoplasmic reticulum protein implicated in chaperoning peptides to major histocompatibility of class I is an aminopeptidase

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7 January 2021

GRP94-associated enzymatic activities. Resolution by chromatographic fractionation

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7 January 2021

Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase

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7 January 2021

Characterization of recombinant human adipocyte-derived leucine aminopeptidase expressed in Chinese hamster ovary cells

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7 January 2021

Genomic organization of the human adipocyte-derived leucine aminopeptidase gene and its relationship to the placental leucine aminopeptidase/oxytocinase gene

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7 January 2021

Molecular characterization of a puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP

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7 January 2021

Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling

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7 January 2021

Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles

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7 January 2021

Human placental leucine aminopeptidase/oxytocinase. A new member of type II membrane-spanning zinc metallopeptidase family

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7 January 2021

Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension

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7 January 2021

A mouse orthologue of puromycin-insensitive leucyl-specific aminopeptidase is expressed in endothelial cells and plays an important role in angiogenesis

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7 January 2021

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

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7 January 2021

The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release

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7 January 2021

Structural basis for the activation of 20S proteasomes by 11S regulators

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7 January 2021

Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes.

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7 January 2021

Preparation of microsomal membranes for cotranslational protein translocation

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7 January 2021

Oligomeric complexes involved in translocation of proteins across the membrane of the endoplasmic reticulum

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7 January 2021

Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody

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7 January 2021

Identifiers

DOI

10.1038/NI859

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017