(Q28137774)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557102%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

review article

1 reference

title

PKR; a sentinel kinase for cellular stress (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557102%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557102%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

B R Williams

series ordinal

1

0 references

language of work or name

English

0 references

publication date

1 November 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557102%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557102%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557102%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557102%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

6112-6120

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557102%20AND%20SRC:MED&resulttype=core&format=json

Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR.

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

NMR solution structure of a dsRNA binding domain from Drosophila staufen protein reveals homology to the N-terminal domain of ribosomal protein S5

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Mutations in the Double-stranded RNA-activated Protein Kinase Insert Region That Uncouple Catalysis from eIF2α Binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Involvement of Double-stranded RNA-activated Protein Kinase in the Synergistic Activation of Nuclear Factor-κB by Tumor Necrosis Factor-α and γ-Interferon in Preneuronal Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Potential Alu function: regulation of the activity of double-stranded RNA-activated kinase PKR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

The Double-Stranded RNA-Dependent Protein Kinase PKR: Structure and Function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Structure and regulation of eukaryotic initiation factor eIF-2. Sequence of the site in the alpha subunit phosphorylated by the haem-controlled repressor and by the double-stranded RNA-activated inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Double-stranded-RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Two functionally distinct RNA-binding motifs in the regulatory domain of the protein kinase DAI

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Expression of the double-stranded RNA-dependent protein kinase (p68) in human breast tissues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

The double-stranded RNA-dependent protein kinase is also activated by heparin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Structure of the dsRNA binding domain of E. coli RNase III.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Double-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Interactions between double-stranded RNA regulators and the protein kinase DAI

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Mechanism of interferon action motif I of the interferon-induced, RNA-dependent protein kinase (PKR) is sufficient to mediate RNA-binding activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Mutational analysis of the double-stranded RNA (dsRNA) binding domain of the dsRNA-activated protein kinase, PKR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

A synthetic peptide substrate for initiation factor-2 kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Mechanism of interferon action. Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

The ER-overload response: activation of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

PACT, a protein activator of the interferon-induced protein kinase, PKR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Molecular basis of double-stranded RNA-protein interactions: structure of a dsRNA-binding domain complexed with dsRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Abnormal levels and minimal activity of the dsRNA-activated protein kinase, PKR, in breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Induction of Oxidative Stress by Okadaic Acid Is Required for Activation of Transcription Factor NF-κB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

c-Myc is a major mediator of the synergistic growth inhibitory effects of retinoic acid and interferon in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Translational control perks up

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

A conserved double-stranded RNA-binding domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

staufen, a gene required to localize maternal RNAs in the Drosophila egg

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

How cells respond to interferons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Double-stranded RNA-independent dimerization of interferon-induced protein kinase PKR and inhibition of dimerization by the cellular P58IPK inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: a new face of death?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Inhibition of double-stranded RNA- and tumor necrosis factor alpha-mediated apoptosis by tetratricopeptide repeat protein and cochaperone P58(IPK)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

The role of the dsRNA-activated kinase, PKR, in signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Tumor suppressor p53 as a component of the tumor necrosis factor-induced, protein kinase PKR-mediated apoptotic pathway in human promonocytic U937 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Cell cycle regulation of the double stranded RNA activated protein kinase, PKR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Expression of p68 protein kinase and its prognostic significance during IFN-alpha therapy in patients with carcinoid tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203127

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203127

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10557102%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 November 2019

1004663973

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017