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LC/MS applications in drug development
scientific article (publication date: 1999)
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review article
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Europe PubMed Central
title
LC/MS applications in drug development
(English)
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author name string
M S Lee
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1
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E H Kerns
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2
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language of work or name
English
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publication date
1999
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PubMed
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Mass Spectrometry Reviews
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volume
18
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issue
3-4
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page(s)
187-279
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cites work
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Proposal for a common nomenclature for sequence ions in mass spectra of peptides
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21 January 2018
Predictive strategy for the rapid structure elucidation of drug degradants
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21 January 2018
Investigation of the CNS penetration of a potent 5-HT2a receptor antagonist (MDL 100,907) and an active metabolite (MDL 105,725) using in vivo microdialysis sampling in the rat.
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21 January 2018
Purification and determination of intact molecular mass by electrospray ionization mass spectrometry of the photosystem II reaction center subunits
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21 January 2018
Rapid 'de novo' peptide sequencing by a combination of nanoelectrospray, isotopic labeling and a quadrupole/time-of-flight mass spectrometer.
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21 January 2018
High throughput liquid chromatography/mass spectrometry bioanalysis using 96-well disk solid phase extraction plate for the sample preparation.
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21 January 2018
Coupling capillary high-performance liquid chromatography to matrix-assisted laser desorption/ionization mass spectrometry and N-terminal sequencing of peptides via automated microblotting onto membrane substrates.
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21 January 2018
Automated mass spectrometry imaging with a matrix-assisted laser desorption ionization time-of-flight instrument
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21 January 2018
'Metabolic mapping' of drugs: rapid screening techniques for xenobiotic metabolites with m.s./m.s. techniques
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21 January 2018
The identification of peptide modifications derived from gel-separated proteins using electrospray triple quadrupole and ion trap analyses
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21 January 2018
A liquid chromatography/electrospray mass spectrometric study on the post-transcriptional modification of tRNA.
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21 January 2018
Open access atmospheric pressure chemical ionization Mass spectrometry for routine sample analysis
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21 January 2018
Sildenafil (VIAGRATM), a potent and selective inhibitor of type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction
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21 January 2018
Application of liquid chromatography-mass spectrometry(n) analyses to the characterization of novel glyburide metabolites formed in vitro
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21 January 2018
Pulsed ultrafiltration mass spectrometry: a new method for screening combinatorial libraries.
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21 January 2018
Profiling impurities and degradants of butorphanol tartrate using liquid chromatography/mass spectrometry and liquid chromatography/tandem mass spectrometry substructural techniques
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21 January 2018
Studies on the metabolism of omeprazole in the rat using liquid chromatography/ionspray mass spectrometry and the isotope cluster technique with [34S]omeprazole
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21 January 2018
Electrospray-ionization mass spectrometry of intact intrinsic membrane proteins
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21 January 2018
Analytical properties of the nanoelectrospray ion source
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21 January 2018
Deconvolution of combinatorial libraries for drug discovery: experimental comparison of pooling strategies
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21 January 2018
Peptide mass maps: a highly informative approach to protein identification
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21 January 2018
Mass spectrometry and the age of the proteome
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21 January 2018
Method to compare collision-induced dissociation spectra of peptides: potential for library searching and subtractive analysis
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21 January 2018
Database searching using mass spectrometry data
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21 January 2018
Tandem mass spectrometry: quadrupole and hybrid instruments
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21 January 2018
Identification of in vitro metabolites of Indinavir by "intelligent automated LC-MS/MS" (INTAMS) utilizing triple quadrupole tandem mass spectrometry.
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21 January 2018
A double-blind comparison of oral butorphanol and codeine
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21 January 2018
The observation of non-covalent interactions in solution by electrospray ionization mass spectrometry: Promise, pitfalls and prognosis
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21 January 2018
Perfusion chromatography
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21 January 2018
Pyripyropenes, novel inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus. I. Production, isolation, and biological properties
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Identifiers
DOI
10.1002/(SICI)1098-2787(1999)18:3/4<187::AID-MAS2>3.0.CO;2-K
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PubMed publication ID
10568041
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